Chemicals

7Acetyltaxol CAS 92950395 China Suppliers and Factory Price

Buy high-purity 7-Acetyltaxol CAS 92950-39-5 from leading China suppliers. Our factory provides this semi-synthetic paclitaxel derivative as a critical reference standard for impurity profiling and oncology SAR studies, ensuring global pharmaceutical compliance.

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.

7-Acetyltaxol (CAS NO. 92950-39-5) is a high-purity semi-synthetic taxane derivative designed for advanced biomedical research. As a potent microtubule stabilizer and mitotic inhibitor, it serves as a critical tool in oncological studies, mimicking the biological activity of paclitaxel by binding to the beta-tubulin subunit to prevent chromosomal segregation and trigger apoptosis in rapidly dividing cells.

Primarily utilized as a certified reference material, 7-Acetyltaxol is indispensable for pharmaceutical developers and analytical chemists. It is widely employed in HPLC and Mass Spectrometry (MS) to establish impurity profiles and ensure the quality of paclitaxel APIs, providing a reliable benchmark for quantifying related substances and evaluating the cytotoxic potential of novel taxane structural optimizations.

Detailed Parameters

Product Name7-Acetyltaxol CAS NO.92950-39-5
Molecular FormulaC49H53NO15 Molecular Weight895.94 g/mol
Purity (RP-HPLC)≥98% AppearanceWhite to off-white amorphous powder
SolubilitySoluble in DMSO, Chloroform, Ethyl Acetate Endotoxin≤ 5 EU/mg
StorageStore at -20°C, protected from light MOQ1g

Key Advantages

Ultra-High Purity

Certified ≥98% purity via RP-HPLC, ensuring precise and reproducible results for sensitive analytical research.

Rapid US Delivery

Strategically stocked in USA warehouses to minimize transit times and ensure rapid project turnaround.

GMP Compliance

Produced by partners utilizing GMP-compliant systems with standardized quality control across all stages.

Full Traceability

Complete documentation provided, including COA, HPLC purity reports, and MS chromatograms for every batch.

Bio-Active Standard

Demonstrated IC50 values around 60 nM, serving as a gold standard for microtubule dynamics benchmarking.

Custom Packaging

Professional vacuum-sealed, light-protected packaging tailored to maintain stability during global transit.

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Management Platforms

Raw Material Control

Strict procurement protocols ensuring only pharmaceutical-grade precursors enter the synthesis chain.

Synthesis Precision

Advanced semi-synthetic processes to maintain structural integrity at the C-7 hydroxyl modification site.

Quality Validation

Multi-stage testing using High-Performance Liquid Chromatography and Mass Spectrometry.

Cold Chain Logistics

Specialized -20°C shipping environment to prevent degradation of heat-sensitive taxanes.

Batch Traceability

Unique batch numbering system linking every gram to its specific synthesis and testing record.

Regulatory Support

Provision of DMF and FDA-compliant documentation to support international trade and research.

Investment Return Comparison

FeatureStandard GradeGlobalTech Premium
Purity Level≥95%≥98% (Certified)
DocumentationBasic COACOA + HPLC + MS Report
Delivery Speed14-21 Days3-5 Days (US Stock)
StabilityVariableHigh (Strict -20°C Control)
Technical SupportLimitedProfessional Analytical Support

Frequently Asked Questions

Q: What is the primary application of 7-Acetyltaxol in pharmaceutical manufacturing?

It is primarily used as a certified reference standard for the identification and quantification of impurities in Paclitaxel APIs, helping manufacturers maintain strict quality control via HPLC and MS.

Q: How does 7-Acetyltaxol differ biologically from Paclitaxel?

While it is an acetylated derivative at the C-7 position, preclinical data shows it retains core cytotoxic potential and the ability to promote microtubule assembly similar to Paclitaxel.

Q: What are the recommended storage conditions for this compound?

To ensure stability and prevent degradation, 7-Acetyltaxol must be stored at -20°C in a tightly sealed container, protected from both moisture and direct light.

Q: Can 7-Acetyltaxol be used for clinical therapeutic purposes?

No, this product is strictly indicated for non-clinical, in vitro research applications and laboratory analysis only.

Q: Which solubility solvents are most effective for this taxane derivative?

7-Acetyltaxol is highly soluble in DMSO, Chloroform, and Ethyl Acetate, but it is insoluble in water.

Q: How does GlobalTech ensure the purity of its Pharmaceutical Intermediates?

We employ a rigorous quality management system utilizing GMP-compliant production and third-party validation, providing full HPLC and MS chromatograms for every batch.

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