Berberine CAS NO.2086-83-1

TECHNICAL SPECIFICATIONS

Mechanism of Action

Berberine exerts its multifaceted biological effects primarily through the activation of AMP-activated protein kinase (AMPK), a central regulator of cellular energy homeostasis that enhances glucose uptake and fatty acid oxidation while inhibiting gluconeogenesis, coupled with its ability to modulate the gut microbiome by promoting beneficial bacterial populations and reducing pathogenic species, alongside its interaction with microbial membrane integrity and its role in suppressing pro-inflammatory signaling pathways such as NF-κB and NLRP3 inflammasome, thereby contributing to its systemic metabolic and immune-modulating properties.

Product Indications

This versatile alkaloid is indicated for use in scientific research exploring metabolic disorders such as type 2 diabetes, obesity, and hyperlipidemia, as well as for investigating its potential in gastrointestinal health, antimicrobial applications, and neuroprotective studies, making it highly relevant for pharmaceutical developers, nutraceutical formulators, and academic researchers seeking natural compounds with proven efficacy in addressing chronic inflammatory conditions and supporting overall physiological homeostasis.

Clinical Efficacy of Product

Clinical studies have demonstrated that berberine exhibits comparable efficacy to certain conventional pharmaceuticals in lowering blood glucose levels and improving lipid profiles, with significant reductions in HbA1c, fasting blood glucose, total cholesterol, and LDL cholesterol observed in diabetic and hyperlipidemic patient populations, while also showing promise in alleviating symptoms of metabolic syndrome, reducing inflammation markers, and improving gut barrier function, thereby validating its therapeutic potential as a multi-targeted natural agent for managing chronic metabolic and inflammatory diseases.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510