Chemicals

4-Acetyl-2-methylbenzoic acid CAS NO.55860-35-0

<p><strong>4-Acetyl-2-methylbenzoic acid</strong> is a high-purity aromatic carboxylic acid derivative, appearing as a white to yellowish crystalline powder, primarily utilized as a versatile organic synthesis building block and a critical pharmaceutical intermediate for advanced chemical manufacturing. Characterized by the presence of both a reactive carboxyl group and an acetyl ketone moiety on a methyl-substitute…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Oroxylin A 7-O-glucuronide
CAS NO.
336948-76-2
Appearance
Off-white to light yellow powder
Molecular Formula
C22H20O11
Molecular Weight
460.39 g/mol
Purity (RP-HPLC)
≥98% 
Solubility

Soluble in water, DMSO; insoluble in ethanol, acetone, chloroform

Endotoxin
≤10 EU/mg 
Biological Activity
Anti-tumor activity; Anti-inflammatory; Neuroprotective effects
Storage Conditions
-20°C, protected from light, dry and sealed
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

4-Acetyl-2-methylbenzoic acid functions as a key reactive intermediate in multi-step organic synthesis, where its chemical behavior is defined by the distinct reactivities of its functional groups to facilitate targeted molecular coupling and cyclization. The carboxylic acid group readily undergoes esterification with alcohols or amidation with amines under catalytic conditions, while the adjacent acetyl carbonyl can participate in nucleophilic addition, condensation reactions (such as Knoevenagel condensation), or serve as a precursor for heterocycle formation like isoxazoline rings. In the context of material science, the compound acts as a multifunctional linker or ligand, capable of chelating metal ions to form coordination polymers and Metal-Organic Frameworks (MOFs), thereby enabling the precise assembly of porous structures used in gas storage, separation, and catalysis at the molecular level.

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2.PRODUCT INDICATIONS

4-Acetyl-2-methylbenzoic acid is indicated for use in pharmaceutical synthesis, particularly as the core structural fragment for producing isoxazoline-based ectoparasiticides such as Fluralaner and Fluxametamide, which are widely used in veterinary medicine to control fleas, ticks, and mites on companion animals. It is also extensively employed by agrochemical researchers developing novel amide-class insecticides and herbicides, as well as by medicinal chemists synthesizing Non-Steroidal Anti-Inflammatory Drug (NSAID) analogs and tyrosine kinase inhibitors. Furthermore, the product caters to material scientists and organic chemists engaged in the design of OLED (Organic Light Emitting Diode) materials, fluorescent dyes, cosmetic raw materials, and advanced organic semiconductor precursors, serving as a fundamental starting material for laboratory-scale research and industrial-scale production processes.
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3.CLINICAL EFFICACY OF PRODUCT

4-Acetyl-2-methylbenzoic acid has demonstrated high synthetic efficacy and reliability in the industrial-scale production of Fluralaner, where it serves as one of the three essential fragments that condense and cyclize to form the biologically active isoxazoline ring system with potent insecticidal properties. Laboratory synthesis routes confirm its high reactivity and yield in condensation reactions with trifluoromethyl ketones, followed by oxime cyclization, consistently producing the target intermediates with purity levels suitable for subsequent amide coupling steps. Its structural integrity and functional group compatibility allow for efficient derivatization without unwanted side reactions, making it a robust and dependable intermediate that meets stringent pharmaceutical grade requirements for the successful development of next-generation parasiticide therapies and functional fine chemicals.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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