Polyphyllin VI  CAS NO.55916-51-3

TECHNICAL SPECIFICATIONS

1.Mechanism of Action

Polyphyllin VI exerts its multifaceted biological effects primarily by inducing apoptosis in tumor cells through the activation of the intrinsic mitochondrial pathway, involving the regulation of Bcl-2 family proteins and the generation of reactive oxygen species. Additionally, it modulates key signaling cascades such as the PI3K/Akt and JAK/STAT pathways, thereby inhibiting cancer cell proliferation, migration, and angiogenesis, while also displaying significant anti-inflammatory effects by suppressing NF-κB and MAPK signaling in immune cells.

2.Product Indications

This compound is specifically indicated for use in scientific research aimed at exploring novel anti-cancer therapies, understanding the mechanisms of tumorigenesis, and developing anti-inflammatory agents. It is an essential tool for academic and pharmaceutical researchers investigating cell death pathways, immune modulation, and the treatment of chronic inflammatory diseases, as well as for those screening natural products for potential drug leads.

3.Clinical Efficacy of Product

While Polyphyllin VI itself is primarily a research chemical used in preclinical settings, its efficacy has been demonstrated in numerous in vitro and in vivo studies where it has shown potent tumor growth inhibition across multiple cancer types, including lung, liver, and breast cancer. Preclinical data suggest that it can enhance the efficacy of conventional chemotherapeutic agents and reduce tumor metastasis, highlighting its promise as a lead compound for future clinical development in oncology and related therapeutic areas.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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