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Chemicals
Vasicinone CAS NO.486-64-6
<p>Vasicinone is a high-purity quinazoline alkaloid naturally derived from the leaves of Adhatoda vasica (Malabar nut) and Peganum harmala, supplied as a premium research-grade reagent for scientists exploring plant-based bioactive compounds, respiratory pharmacology, and neurosciences. It is distinguished by its unique pyrroloquinazoline structure, making it an essential reference standard for researchers in natura…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Vasicinone |
| CAS NO. | 486-64-6 |
| Appearance | Fine off-white to light yellow crystalline powder |
| Molecular Formula | C11H10N2O2 |
| Molecular Weight | 202.21 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in DMSO, Ethanol, and Methanol; slightly soluble in water |
| Endotoxin | < 10 EU/mg |
| Biological Activity | Bronchodilator, antimicrobial, anti-inflammatory, and potential anticancer properties |
| Storage Conditions | Store at -20°C, protected from light and moisture. Keep container tightly sealed. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The primary biological action of Vasicinone involves the induction of apoptosis in cancer cells by increasing the expression of caspase enzymes and disrupting the mitochondrial pathway through cytochrome c release, which leads to cell cycle arrest via the regulation of cyclins and CDKs. Concurrently, it exerts significant neuroprotective effects by suppressing the MAPK signaling pathway, which attenuates reactive oxygen species (ROS) accumulation and reduces the percentage of apoptotic cells in models of oxidative stress-induced injury, such as Parkinson’s disease research. Furthermore, in respiratory research settings, it functions as a bronchodilator and respiratory stimulant that relaxes airway smooth muscles and exhibits anticholinesterase activity, showcasing its versatile pharmacological interference at the cellular and enzymatic levels.
2.PRODUCT INDICATIONS
This product is strictly indicated for in vitro research, phytochemical analysis, and controlled laboratory use, targeting a specialized audience that includes pharmacologists, botanists, neuroscientists, and respiratory disease researchers rather than clinical or therapeutic application. It is ideally suited for professionals developing analytical methods (such as HPLC or HPTLC) to quantify alkaloids in medicinal plants, as well as for cell biologists modeling the cytoprotective effects of natural compounds against neurodegeneration and Parkinson’s disease. Additionally, it serves as a vital pharmacological tool for scientists screening novel anti-cancer agents or studying the biochemical basis of traditional herbal medicine remedies used for asthma, bronchitis, cough relief, and hepatoprotection against toxin-induced liver damage.
3.CLINICAL EFFICACY OF PRODUCT
As a non-therapeutic chemical standard, Vasicinone does not possess clinical efficacy in treating patients, yet its research utility is highly validated in preclinical models where it effectively demonstrates potent antitussive, expectorant, and bronchodilating properties comparable to established respiratory therapeutics. In various controlled experimental settings, it has proven instrumental in confirming the hepatoprotective capabilities and free radical scavenging activities of quinazoline alkaloids, successfully replicating anti-inflammatory, anti-proliferative, and neuroprotective responses that correlate with the ethnomedical use of its source plants. Its reliability in these research contexts allows scientists to accurately gauge the potential of natural alkaloids in mitigating neuronal apoptosis, carcinoma progression, and bronchial inflammation, thereby providing robust foundational data for future drug discovery and phytopharmaceutical development.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:consult@huanqiukeji9.com
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