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Chemicals
Alisol C CAS NO.30489-27-1
<p><div class="ybc-p"></div></p><div class="ybc-p">Alisol C is a prototypical triterpenoid compound isolated from the rhizomes of <em>Alisma orientale</em>(water plantain), supplied as a high-purity crystalline powder strictly for non-clinical laboratory research and phytochemical analysis. It serves as a vital reference standard and a lead compound for scientists investigating the pharmacological basis of tradition…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Alisol C |
| CAS NO. | 30489-27-1 |
| Appearance | White to off-white amorphous powder |
| Molecular Formula | C30H46O5 |
| Molecular Weight | 486.68 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in methanol, ethanol, DMSO; insoluble in water |
| Endotoxin | ≤10 EU/mg |
| Biological Activity | Potent diuretic activity, anti-hepatitis B virus (HBV) activity, anti-inflammatory, and potential anti-cancer effects |
| Storage Conditions | Store at - 20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The primary biological mechanism of Alisol C involves the modulation of critical metabolic and inflammatory signaling pathways, most notably by improving glucose uptake in hepatocytes (such as HepG2 cells) to help regulate insulin sensitivity and glycolytic flux. It exerts hepatoprotective and lipid-modulating effects by interacting with the Farnesoid X Receptor (FXR) and regulating downstream targets related to cholesterol and triglyceride metabolism, including CYP7A1, SREBP-1c, and PPARα. Additionally, the compound mitigates oxidative injury and inflammation by suppressing the NF-κB signaling cascade and reducing the production of reactive oxygen species (ROS) and pro-inflammatory cytokines (such as TNF-α and IL-6), while also demonstrating the ability to induce apoptosis in certain cancer cell lines through the regulation of Bcl-2 family proteins and caspase activation.
2.PRODUCT INDICATIONS
This product is indicated for preclinical research applications targeting professionals in hepatology, endocrinology, pharmacology, and oncological studies, including researchers modeling non-alcoholic fatty liver disease (NAFLD), hyperlipidemia, diabetes, and chemical-induced hepatotoxicity. It is particularly suitable for metabolic scientists studying the therapeutic material basis of hypoglycemic and lipid-lowering activities in traditional medicines, as well as toxicologists evaluating the safety profiles and potential nephrotoxicity of Alismaconstituents at specific dosages. Furthermore, it serves as an essential standard for the quality control, fingerprint analysis, and chromatographic method development (HPLC/MS) of botanical extracts, and is applicable for cell biologists conducting screenings to evaluate the direct impact of triterpenoids on cellular viability, metabolism, and stress resistance in controlled laboratory settings.
3.CLINICAL EFFICACY OF PRODUCT
As a raw botanical reference standard not formulated for human therapeutic use, Alisol C does not possess approved clinical efficacy, yet it demonstrates significant bioactive potential in extensive preclinical in vitro and animal model studies. Experimental data indicate that it effectively improves glucose tolerance and enhances cellular glucose uptake in insulin-resistant models, while also showing protective effects against liver injuries induced by carbon tetrachloride (CCl₄) or D-galactosamine by preserving antioxidant enzyme activities and reducing inflammatory infiltration. Additionally, research highlights its capacity to inhibit tumor cell proliferation (e.g., in HepG2 and MCF-7 lines) and modulate lipid accumulation, validating its strong pharmacological profile as a research tool and a promising lead structure for metabolic and hepatic drug discovery, rather than serving as a direct clinical treatment for patients.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Iridoid, Natural Product, Anti-inflammatory, Antioxidant, NF-κB Pathway, MAPK Pathway, Phytochemical, Research Chemical, Glucoside, Herbal Standard.
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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