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Chemicals
8-Epi-Loganic acid CAS NO.82509-41-9
<p><div class="ybc-p"></div></p><div class="ybc-p">8-Epi-Loganic acid is a naturally derived iridoid glucoside primarily isolated from plant species such as <em>Linaria cymbalaria</em>and <em>Valeriana officinalis</em>, supplied as a high-purity white crystalline powder or DMSO solution strictly for laboratory research use. It serves as a valuable chemical standard and a lead compound in pharmacological screening, o…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | 8-Epi-Loganic acid |
| CAS NO. | 82509-41-9 |
| Appearance | White to off - white crystalline powder |
| Molecular Formula | C16H24O10 |
| Molecular Weight | 376.36 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in DMSO, chloroform, absolute alcohol; slightly soluble in oil |
| Endotoxin | ≤10 EU/mg |
| Biological Activity | Exhibits anti - inflammatory and antioxidant activities; modulates NF - κB and MAPK signaling pathways |
| Storage Conditions | Store at - 20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The primary biological mechanism of 8-Epi-Loganic acid involves the suppression of key inflammatory signaling cascades, specifically by inhibiting the activation of nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) pathways in macrophages. By intervening in these pathways, the compound effectively reduces the expression and production of pro-inflammatory mediators, including nitric oxide (NO), prostaglandin E2 (PGE2), and cytokines such as TNF-α and IL-6. Additionally, its structural properties allow it to exhibit antioxidant capabilities, helping to mitigate oxidative stress and prevent cellular apoptosis induced by external stimuli, thereby modulating the cellular environment at a molecular level without directly interacting with receptor binding sites typical of synthetic drugs.
2.PRODUCT INDICATIONS
This product is indicated for use in scientific research focused on inflammation, oxidative stress, neuroprotection, and metabolic disorders, targeting researchers and laboratories studying chronic diseases such as arthritis, neurodegeneration, and diabetes. It is particularly suited for professionals developing anti-inflammatory agents or exploring natural product chemistry, serving as a reference standard for the quality control of herbal medicines or as a starting material for semi-synthetic derivatization to improve bioavailability. Furthermore, it is applicable in studies involving enzyme inhibition, such as alpha-glucosidase assays, and is intended for use by qualified personnel in controlled settings to ensure accurate experimental outcomes related to cellular physiology and pathology.
3.CLINICAL EFFICACY OF PRODUCT
As a raw chemical reagent not formulated as a finished therapeutic drug, 8-Epi-Loganic acid does not possess clinical efficacy data derived from human trials but demonstrates significant bioactive potential in preclinical in vitro and animal models. Experimental studies indicate that it effectively ameliorates LPS-induced inflammatory responses and shows promise in reducing neuronal damage and liver injury in specific pathological models, validating its potency as a pharmacological agent at the cellular level. These research-grade findings suggest strong efficacy in mitigating specific biochemical markers of disease in controlled environments, providing a foundation for further drug development rather than serving as a direct treatment for patient populations.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Iridoid, Natural Product, Anti-inflammatory, Antioxidant, NF-κB Pathway, MAPK Pathway, Phytochemical, Research Chemical, Glucoside, Herbal Standard.
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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