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Chemicals
All Trans-Retinal CAS NO.116-31-4
<p>All Trans-Retinal, also known as Retinaldehyde or Vitamin A aldehyde, is a high-purity yellow crystalline powder primarily supplied for advanced cosmetic formulation, vision science research, and biochemical studies. As a direct metabolic precursor to retinoic acid, it occupies a critical position in the vitamin A metabolic pathway, offering formulators a potent yet relatively low-irritation alternative to tradit…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | All Trans-Retinal |
| CAS NO. | 116-31-4 |
| Appearance | Bright yellow crystalline powder |
| Molecular Formula | C20H28O |
| Molecular Weight | 284.44 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in DMSO, chloroform, absolute alcohol; slightly soluble in oil |
| Endotoxin | ≤10 EU/mg |
| Biological Activity | Activates retinoic acid receptors (RAR/RXR); Regulates epidermal cell differentiation and proliferation |
| Storage Conditions | -20°C, protected from light, dry and sealed |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The biological activity of All Trans-Retinal is defined by its rapid single-step enzymatic conversion into retinoic acid directly within the epidermis, where it then binds to nuclear retinoic acid receptors (RARs and RXRs) to modulate gene expression responsible for cell turnover, collagen synthesis, and keratinocyte differentiation. In dermatological applications, this mechanism accelerates the shedding of dead skin cells and boosts dermal matrix production while maintaining a favorable irritation profile due to the skin’s regulated, rate-limited conversion process. Simultaneously, in ocular and neurological research, the molecule functions as a vital chromophore that undergoes light-induced isomerization to trigger G-protein signaling cascades in visual pigments, or serves as a cofactor in optogenetic tools to enable precise light-controlled activation of engineered ion channels in neuronal studies.
2.PRODUCT INDICATIONS
This product is indicated for use by professional cosmetic chemists, private label skincare manufacturers, and biochemical research laboratories engaged in dermatological product development or cellular biology studies. It is ideally suited for formulators creating high-performance serums, creams, and lotions aimed at reducing fine lines, hyperpigmentation, and acne breakouts, typically incorporated at concentrations ranging from 0.05% to 0.15% in stabilized, anhydrous bases. Additionally, it serves as an essential analytical reference standard for quantifying vitamin A metabolites and as a specialized reagent for academic and pharmaceutical researchers investigating retinal degeneration, visual cycle biochemistry, and the development of light-sensitive proteins for advanced neuromodulation therapies.
3.CLINICAL EFFICACY OF PRODUCT
While All Trans-Retinal is marketed as a raw cosmetic active ingredient and research chemical rather than a finished clinical drug, its efficacy is well-supported by comparative dermatological studies showing it works up to 11 times faster than retinol in improving skin texture and reducing photoaging signs due to its proximity to active retinoic acid. Clinical observations confirm that topical formulations containing retinaldehyde significantly increase epidermal thickness, stimulate collagen types I and III, and reduce acne lesions with notably better tolerability and less erythema than prescription retinoic acid, making it suitable for sensitive skin applications. These validated performance outcomes, combined with its established role in the visual cycle, make it a high-value ingredient for brands seeking clinically inspired, consumer-friendly anti-aging solutions without the regulatory constraints of prescription-strength vitamin A analogs.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: All Trans-Retinal, Retinaldehyde, Vitamin A aldehyde, Retinene, Retinal, Anti-aging active ingredient, Retinoid, Visual chromophore, Cosmetic raw material, Skincare supplier.
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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