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Chemicals
β-Endorphin (6-31), human CAS NO.77761-27-4
<p>β-Endorphin (6-31), human is a bioactive C-terminal fragment derived from the endogenous opioid peptide β-Endorphin. This 26-amino acid peptide retains the core receptor-binding region, functioning as a potent ligand for μ-opioid receptors (MOR). It is widely utilized in neuroscience and pharmacology research to study pain signaling pathways, stress responses, and the molecular mechanisms of opioid receptor activ…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | β-Endorphin (6-31), human |
| CAS NO. | 77761-27-4 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₃₁H₂₁₈N₃₄O₄₀ |
| Molecular Weight | 2968.4g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in 1M acetic acid, DMSO, or deionized water |
| Endotoxin | ≤1 EU/mg |
| Biological Activity | Potent agonist for μ-opioid receptors (MOR) |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The peptide exerts its effects by selectively binding to μ-opioid receptors in the central and peripheral nervous systems. Upon binding, it activates Gi/o protein-coupled signaling pathways, leading to the inhibition of adenylate cyclase and a reduction in intracellular cAMP levels. This action results in the hyperpolarization of neurons through the modulation of ion channels (inhibition of voltage-gated calcium channels and activation of potassium channels), ultimately suppressing neurotransmitter release and blocking pain signal transmission along nociceptive pathways.
2.PRODUCT INDICATIONS
This product is specifically indicated for research use only (RUO), targeting scientists in the fields of neuropharmacology and pain research. It is employed in a variety of experimental applications, including receptor binding assays, signal transduction studies, and the investigation of stress-related behaviors. Researchers also use it to explore the crosstalk between the nervous and immune systems, as well as in the screening and development of novel analgesic compounds with potentially reduced side-effect profiles.
3.CLINICAL EFFICACY OF PRODUCT
As a research-grade biochemical reagent, β-Endorphin (6-31) is not intended for direct clinical or therapeutic use in humans. Its efficacy is demonstrated in preclinical research settings, where it has been shown to produce significant analgesic and anti-nociceptive effects in animal models. These studies help elucidate the role of endogenous opioid systems in pain management and contribute to the foundational knowledge required for future drug discovery efforts aimed at treating chronic pain conditions.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85244969439
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Global Technology Co., Ltd.
