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Chemicals
Cholecystokinin-33 (10-20) (bovine, porcine) CAS NO.100900-23-0
<p>Cholecystokinin-33 (10-20) (bovine, porcine) is an 11-amino acid bioactive fragment derived from the central region of the full-length cholecystokinin-33 (CCK-33) peptide. This synthetic peptide retains key receptor-binding motifs and is widely utilized in gastrointestinal and neurological research to study CCK receptor signaling without the complexity of the full-length hormone. It serves as a critical tool for …
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Cholecystokinin-33 (10-20) (bovine, porcine) |
| CAS NO. | 100900-23-0 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C54H90N16O18 |
| Molecular Weight | 1287.4g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, 0.1 M acetic acid, or 10% DMSO solution |
| Endotoxin | ≤1 EU/mg |
| Biological Activity | Agonist for CCK1 and CCK2 receptors; stimulates gallbladder contraction, pancreatic enzyme secretion, and modulates appetite and anxiety-like behavior in rodent models |
| Storage Conditions | Store at -20°C, protected from light and moisture; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The peptide functions as an agonist for both CCK1 (peripheral) and CCK2 (central) receptors, though with potentially modified affinity compared to shorter sulfated forms. Upon binding, it activates Gq protein-coupled signaling pathways, leading to phospholipase C activation, intracellular calcium mobilization, and downstream kinase cascades. This results in the stimulation of gallbladder contraction, pancreatic enzyme secretion, and modulation of dopamine and serotonin neurotransmission in the brain, influencing satiety and emotional responses.
2.PRODUCT INDICATIONS
The peptide functions as an agonist for both CCK1 (peripheral) and CCK2 (central) receptors, though with potentially modified affinity compared to shorter sulfated forms. Upon binding, it activates Gq protein-coupled signaling pathways, leading to phospholipase C activation, intracellular calcium mobilization, and downstream kinase cascades. This results in the stimulation of gallbladder contraction, pancreatic enzyme secretion, and modulation of dopamine and serotonin neurotransmission in the brain, influencing satiety and emotional responses.
3.CLINICAL EFFICACY OF PRODUCT
In experimental models, Cholecystokinin-33 (10-20) demonstrates efficacy in reducing food intake and stimulating pancreaticobiliary secretions, validating its role in mimicking physiological CCK actions. Studies show it can induce satiety and alter exploratory behavior in rodents, supporting its use as a reliable reagent for elucidating CCK-mediated pathways. While not used directly in human therapy, its consistent bioactivity makes it a valuable standard for translational research.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85296236544
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