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Chemicals
ACTH (3-24), human CAS NO.1036763-00-4
<p>ACTH (3-24), human is a bioactive N-terminal fragment of adrenocorticotropic hormone (ACTH) that retains the core receptor-binding region while lacking the first two amino acids. This synthetic peptide is widely used as a research tool to study the hypothalamic-pituitary-adrenal (HPA) axis and melanocortin receptor signaling without the full steroidogenic potency of the full-length hormone, making it ideal for me…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | ACTH (3-24), human |
| CAS NO. | 1036763-00-4 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₂₄H₁₉₆N₃₈O₂₇S |
| Molecular Weight | 2795.1 g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water or 1x PBS, 1–5 mg/mL |
| Endotoxin | ≤1 EU/mg (LAL test) |
| Biological Activity | Activates melanocortin receptors (e.g., MC2R) with reduced steroidogenic effect; used for receptor binding and signaling studies |
| Storage Conditions | Store at -20°C, protect from light; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The peptide functions as a ligand for melanocortin receptors (MCRs), primarily targeting MC2R in the adrenal cortex. Upon binding, it activates the Gs protein-coupled pathway, leading to adenylate cyclase stimulation and an increase in intracellular cAMP levels. This activation triggers downstream signaling cascades that mimic the early steps of ACTH-induced steroidogenesis, although with potentially altered potency and selectivity compared to the native hormone, allowing researchers to dissect specific receptor interactions.
2.PRODUCT INDICATIONS
This product is indicated for in vitro and in vivo research applications focused on adrenal function, stress response, and HPA axis regulation. It is particularly useful for investigating the role of ACTH fragments in inflammation, immune modulation, and metabolic studies, serving as a critical reagent for scientists studying receptor pharmacology and the development of diagnostic agents for adrenal disorders.
3.CLINICAL EFFICACY OF PRODUCT
In preclinical research models, ACTH (3-24) has demonstrated efficacy in stimulating cAMP production and modulating corticosteroid synthesis pathways. Studies show it can elicit biological responses similar to ACTH in terms of receptor activation and signal transduction, providing a valuable tool for evaluating the therapeutic potential of melanocortin receptor agonists in conditions like adrenal insufficiency and inflammatory diseases.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: ACTH324 #MelanocortinReceptor #HPAaxis #ResearchPeptide #ACTHfragment #MC2R #AdrenalResearch #PeptideSupplier
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85296236544
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