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Chemicals
Baohuoside I CAS NO.113558-15-9
<p>Baohuoside I is a bioactive flavonoid glycoside primarily derived from Epimediumspecies (Horny Goat Weed), serving as a key reference standard and active ingredient in pharmaceutical and nutraceutical research. It is highly valued for its dual anti-tumor and bone-protective properties, targeting cancer metastasis pathways while promoting osteogenic differentiation, making it a versatile compound for oncology, end…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Baohuoside I |
| CAS NO. | 113558-15-9 |
| Appearance | Off-white to light yellow powder |
| Molecular Formula | C₂₇H₃₀O₁₀ |
| Molecular Weight | 514.52 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO, methanol, ethanol; slightly soluble in water; insoluble in hexane |
| Endotoxin | ≤ 5 EU/mg (for cell culture grade) |
| Biological Activity | Anti-metastatic (CXCR4 inhibition), anti-osteoporotic, neuroprotective, and anti-inflammatory effects |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Baohuoside I exerts its effects by targeting the CXCR4 chemokine receptor, inhibiting its expression and downstream NF-κB signaling to suppress cancer cell invasion and metastasis. It induces apoptosis through mitochondrial pathways involving ROS generation, JNK/p38 MAPK activation, and modulation of Bcl-2/Bax ratios. Additionally, it promotes bone formation by inhibiting osteoclast differentiation via MAPK and RANKL pathways, while its neuroprotective effects are mediated through GPER and NLRP3 inflammasome inhibition.
2.PRODUCT INDICATIONS
This product is indicated for preclinical research in oncology (breast, cervical, liver, and pancreatic cancer metastasis models), bone metabolic disorders (osteoporosis, osteoclastogenesis), and neurodegenerative conditions (Parkinson's and Alzheimer's disease). It is also used in traditional medicine research for male vitality and immune modulation, targeting researchers in pharmacology, oncology, and natural product development.
3.CLINICAL EFFICACY OF PRODUCT
In vivo studies demonstrate that Baohuoside I significantly reduces tumor growth and metastasis in xenograft models of breast cancer and hepatocellular carcinoma, with doses around 25 mg/kg showing efficacy. It protects against ovariectomy-induced bone loss by inhibiting osteoclast activity and promotes osteoblast differentiation. Preclinical models of neurodegeneration show improved cognitive function and reduced neuroinflammation, supporting its potential as a multi-target therapeutic agent.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: BaohuosideI #Epimedium #Flavonoid #CXCR4Inhibitor #AntiMetastasis #BoneHealth #OsteoporosisResearch #Neuroprotection
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85296236544
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