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Chemicals
(1S,2R,5R)-(+)-Isomenthol CAS NO.23283-97-8
<p>(1S,2R,5R)-(+)-Isomenthol is a high-purity stereoisomer of menthol, known for its distinct minty aroma and refreshing cooling sensation. It is widely used as a key ingredient in the flavor and fragrance industry, particularly in oral care products, confectionery, and topical formulations where a clean, crisp mint profile is desired. This compound is characterized by its specific spatial configuration, which contr…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | (1S,2R,5R)-(+)-Isomenthol |
| CAS NO. | 23283-97-8 |
| Appearance | White to off-white crystalline solid |
| Molecular Formula | C10H20O |
| Molecular Weight | 156.27 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in ethanol, ether, and lipids; slightly soluble in water |
| Endotoxin | ≤ 0.05 EU/mg |
| Biological Activity | Activates TRPM8 receptors; provides cooling sensation; potential analgesic |
| Storage Conditions | Store in a cool, dry place at 2–8°C; protect from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The primary mechanism of (1S,2R,5R)-(+)-Isomenthol involves interaction with the TRPM8 receptor, a cold-sensitive ion channel expressed in sensory neurons. Upon application, it triggers a calcium influx that generates a physiological cooling sensation without an actual temperature change, effectively masking discomfort and providing a mild analgesic effect. This mechanism is complemented by its ability to modulate sodium channels and GABAergic signaling, contributing to its soothing and mild anesthetic properties in topical applications.
2.PRODUCT INDICATIONS
This product is indicated for use in a wide range of consumer and pharmaceutical applications, including mint flavorings for chewing gum and oral care products, fragrance components in perfumes and cosmetics, and as a cooling agent in topical analgesics and balms. It is particularly suitable for formulations targeting adults seeking relief from minor skin irritations, muscle discomfort, or requiring a refreshing sensory experience. Additionally, it serves as a critical chiral building block for researchers in asymmetric synthesis and fine chemical production.
3.CLINICAL EFFICACY OF PRODUCT
In clinical and user experience terms, (1S,2R,5R)-(+)-Isomenthol demonstrates rapid-onset cooling and mild analgesic effects, effectively relieving sensations of heat and itching in topical preparations. Its inclusion in oral care and confectionery products provides a long-lasting fresh breath sensation, while its role in fragrances offers a stable minty note. Users report significant subjective improvement in nasal airflow perception and throat comfort when used in respiratory products, making it a versatile sensate agent for enhancing product performance.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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