Chemicals

L-(+)-Ergothioneine CAS NO.497-30-3

<p>L-(+)-Ergothioneine (EGT) is a naturally occurring, sulfur-containing amino acid derivative renowned as a "master antioxidant" and longevity vitamin. Sourced primarily from mushrooms via advanced fermentation, this highly stable, water-soluble compound is distinguished by its unique ability to be actively transported into cells via the OCTN1 transporter, where it accumulates to provide sustained protection agains…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.


TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
L-(+)-Ergothioneine
CAS NO.
497-30-3
Appearance
White to off-white powder
Molecular Formula
C₉H₁₅N₃O₂S
Molecular Weight
245.30 g/mol
Purity (RP-HPLC)
≥ 99.0%
Solubility

Soluble in water, slightly soluble in methanol and ethanol; insoluble in non-polar organic solvents

Endotoxin
≤5 EU/mg (LAL test)
Biological Activity
Potent antioxidant; scavenges ROS/RNS, stabilizes mitochondrial function, protects skin, liver, and neural cells from oxidative damage
Storage Conditions
Store at room temperature (≤25°C), dry and protected from light
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

L-Ergothioneine exerts its effects by selectively accumulating in mitochondria and nuclei of high-stress tissues (skin, liver, brain) via the OCTN1 transporter. Unlike many antioxidants, its unique thione structure allows it to act as a stable, non-autoxidizing scavenger of reactive oxygen and nitrogen species (ROS/RNS), chelate pro-oxidant metal ions, and upregulate endogenous antioxidant defenses, thereby protecting DNA, proteins, and lipids from oxidative damage without being rapidly consumed.

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2.PRODUCT INDICATIONS

This ingredient is primarily indicated for incorporation into high-end cosmeceuticals (anti-aging serums, brightening creams, sun care) to combat photoaging and inflammation, as well as nutraceutical supplements targeting cognitive support, metabolic health, and systemic anti-aging for middle-aged and elderly populations seeking to mitigate age-related declines in endogenous antioxidant capacity.

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3.CLINICAL EFFICACY OF PRODUCT

Human clinical trials, including randomized controlled studies, have demonstrated that oral or topical L-Ergothioneine significantly improves skin parameters by reducing melanin index and erythema, enhancing elasticity, and diminishing wrinkles. Research also supports its role in mitigating markers of systemic inflammation and oxidative stress, correlating with potential benefits for cardiovascular and neurological health in aging populations.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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