Chemicals

(±)-Naringenin CAS NO.67604-48-2

<p>(±)-Naringenin is a high-purity racemic mixture of the natural flavonoid Naringenin, primarily derived from citrus fruits like grapefruit and oranges. This product is standardized to meet research-grade quality, offering potent antioxidant, anti-inflammatory, and metabolic regulatory activities. It is widely used in pharmaceutical research, nutraceutical development, and academic studies for investigating metabol…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
(±)-Naringenin
CAS NO.
67604-48-2
Appearance
White to off-white crystalline powder
Molecular Formula
C15H12O5
Molecular Weight
272.25 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility
Soluble in DMSO, methanol, ethanol; slightly soluble in water
Endotoxin< 0.1 EU/mg
Biological Activity
Exhibits antioxidant, anti-inflammatory, and metabolic regulatory effects via modulation of Nrf2, AMPK, and NF-κB pathways
Storage Conditions
Store at 2–8°C in a dry, dark place, tightly sealed
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

(±)-Naringenin exerts its effects through a multi-targeted mechanism, primarily acting as a potent antioxidant by scavenging free radicals and enhancing endogenous defense systems like Nrf2. It modulates key metabolic pathways by activating AMPK and PPARγ, which regulate glucose uptake and lipid metabolism, while also exhibiting anti-inflammatory properties by inhibiting the NF-κB signaling pathway and reducing pro-inflammatory cytokines such as TNF-α and IL-6. Additionally, it influences hormone signaling by selectively interacting with estrogen receptors, contributing to its diverse physiological effects.

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2.PRODUCT INDICATIONS

This product is indicated for research applications in metabolic disorders, including type 2 diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD), where it helps improve insulin sensitivity and reduce hepatic steatosis. It is also utilized in studies on cardiovascular health for its lipid-lowering and anti-atherosclerotic effects, as well as in neuropharmacology for neuroprotective potential against oxidative stress. Furthermore, it serves as a key compound in cancer research for its anti-proliferative and pro-apoptotic properties in hormone-related cancers.

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3.CLINICAL EFFICACY OF PRODUCT

Clinical and pre-clinical studies demonstrate that (±)-Naringenin supplementation significantly improves markers of metabolic health, including reductions in fasting blood glucose, LDL cholesterol, and triglyceride levels. Research highlights its efficacy in ameliorating insulin resistance and liver fat accumulation in subjects with metabolic syndrome, while also showing promise in reducing systemic inflammation and oxidative stress in chronic conditions. Its favorable safety profile and natural origin make it a promising candidate for adjunctive therapy in nutraceutical formulations targeting cardiometabolic wellness.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:(±)-Naringenin, Naringenin, Citrus Flavonoid, Bioflavonoid, Antioxidant, Anti-inflammatory, Metabolic Health, Natural Product, Research Chemical, Pharmaceutical Intermediate, Nutraceutical Ingredient, Grapefruit Extract, Supplier, Manufacturer, Bulk order,  Pharmaceutical.


If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553