Chemicals

6-Demethoxytangeretin CAS NO.6601-66-7

<p>6-Demethoxytangeretin is a high-purity polymethoxyflavone (PMF) extracted from citrus peels, specifically a derivative of tangeretin. As a potent natural flavonoid, it is primarily utilized in the pharmaceutical, nutraceutical, and cosmetic industries for its significant anti-inflammatory and neuroprotective properties. This fine chemical is characterized by its stable yellow powder form and high bioavailability,…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
6-Demethoxytangeretin
CAS NO.
6601-66-7
Appearance
Fine yellow to light brown powder
Molecular Formula
C19H18O6
Molecular Weight
342.34 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility
Soluble in DMSO, methanol, ethanol; slightly soluble in water
Endotoxin≤ 10 EU/mg
Biological Activity
Potent anti-inflammatory, neuroprotective, and anticancer activity
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The compound exerts its effects by modulating key inflammatory signaling pathways. It specifically inhibits the Anaplastic Lymphoma Kinase (ALK) and Mitogen-Activated Protein Kinase (MAPK) pathways, leading to the suppression of pro-inflammatory cytokines such as IL-6 and TNF-α in mast cells. Additionally, it enhances cognitive function by facilitating the cAMP/PKA/ERK/CREB signaling cascade in hippocampal neurons, which promotes synaptic plasticity and memory-related gene transcription.

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2.PRODUCT INDICATIONS

This product is indicated for research and development applications focusing on inflammatory and immune-mediated conditions. It is suitable for developing dietary supplements aimed at reducing chronic inflammation and allergy symptoms, as well as skincare products for soothing irritated skin. Furthermore, its nootropic potential makes it a candidate for formulations designed to support brain health, memory, and cognitive function in aging populations or those under high stress.

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3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that 6-Demethoxytangeretin effectively reduces mast cell activation and the release of histamine and IL-6, confirming its anti-allergic efficacy. In neurological models, it has shown to enhance long-term memory formation and neuronal differentiation. While human clinical trials are still in the early stages, the robust in vitro and in vivo data supports its use as a promising lead compound for developing new therapeutic agents against inflammation-driven diseases and cognitive decline.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553