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Chemicals
Hesperidin methylchalcone CAS NO.24292-52-2
<p>Hesperidin Methylchalcone (HMC, CAS 24292-52-2), also known as <strong>Methyl Hesperidin Chalcone</strong>, is a semi-synthetic, <strong>water-soluble derivative</strong> of the citrus flavonoid Hesperidin. This modification significantly enhances its bioavailability and makes it a premier ingredient for <strong>vascular health</strong> and <strong>anti-inflammatory</strong> applications. As a key component in ve…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Hesperidin Methylchalcone |
| CAS NO. | 24292-52-2 |
| Appearance | Colorless to pale yellow clear liquid |
| Molecular Formula | C₁₅H₂₄ |
| Molecular Weight | 204.35 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in DMF, DMSO, ethanol, chloroform, ether, and petroleum ether; practically insoluble in water Soluble in ethanol:PBS (pH 7.2) (1:2) at 0.3 mg/mL |
| Endotoxin | < 1.0 EU/mg |
| Storage Conditions | 2–8°C, tightly sealed, protected from light and air; avoid prolonged exposure to high temperatures |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
- Vascular Stabilization: It increases capillary resistance and reduces pathological permeability by strengthening the endothelial wall, effectively preventing fluid leakage and edema formation.
- Anti-Inflammatory Signaling: It potently inhibits the NF-κB pathway, reducing the production of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6) and oxidative stress markers.
Analgesic & Antioxidant: It modulates TRPV1 receptors and activates the Nrf2 pathway, contributing to pain relief and protection against free radical damage in tissues
2.PRODUCT INDICATIONS
- Pharmaceuticals: Active ingredient in formulations for Chronic Venous Insufficiency (CVI), varicose veins, hemorrhoidal disease, and edema management.
- Nutraceuticals: Core component of dietary supplements for leg heaviness, capillary fragility, and venous tone improvement.
- Cosmeceuticals: Used in anti-redness (anti-couperose) skincare and antioxidant serums due to its tyrosinase inhibitory and anti-inflammatory properties.
- Analytical Use: High-purity reference standard for HPLC/LC-MS quantification in quality control.
3.CLINICAL EFFICACY OF PRODUCT
- Venous Health: In randomized controlled trials (RCTs), combinations containing HMC (e.g., Cyclo 3 Fort®) significantly improved symptoms of heaviness, pain, and ankle edema in CVI patients, with measurable reductions in limb circumference.
- Capillaroscopic Improvement: Studies confirm its ability to improve microcirculatory parameters and reduce capillary fragility, validating its vasoprotective "Vitamin P" activity.
Symptom Relief: Meta-analyses support its role in rapidly alleviating venous-related discomfort and improving quality of life scores.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510
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