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Chemicals
Cistanoside A CAS NO.93236-42-1
<p>Cistanoside A (CAS 93236-42-1), also known as 肉苁蓉苷 A, is a high-purity phenylethanoid glycoside (PhGs) and a key bioactive marker compound isolated from the traditional Chinese herb <em>Cistanche deserticola</em>(Rou Cong Rong). It is a complex ester glycoside characterized by a phenylethyl alcohol aglycone linked to a trisaccharide moiety (glucose, rhamnose, and apiose). As a major constituent of the "Ginsen…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Cistanoside A |
| CAS NO. | 93236-42-1 |
| Appearance | White to off-white amorphous powder / crystalline powder |
| Molecular Formula | C₃₆H₄₈O₂₀ |
| Molecular Weight | 800.75 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in methanol, ethanol, DMSO, and aqueous methanol; slightly soluble in water; insoluble in n-hexane, petroleum ether |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | A major bioactive phenylethanoid glycoside isolated from Cistanche deserticola Y. C. Ma, exhibits anti-osteoporosis, anti-inflammatory, antioxidant, and neuroprotective activities in preclinical research |
| Storage Conditions | Store at 2-8 °C, sealed, protected from light and moisture; long-term storage at -20 °C is recommended to avoid degradation |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Cistanoside A exerts its effects through multi-target mechanisms. Its hallmark anti-inflammatory action involves the significant reduction of nitric oxide (NO) production in activated macrophages, although it does not directly inhibit iNOS expression or activity, suggesting a unique post-transcriptional or scavenging mechanism. It demonstrates potent anti-osteoporotic effects by promoting osteoblast differentiation and bone formation via the BMP-2/Smad and Wnt/β-catenin signaling pathways. Additionally, it exhibits antioxidant activity by scavenging free radicals and modulating oxidative stress-related pathways, contributing to its neuro- and hepatoprotective benefits.
2.PRODUCT INDICATIONS
TCM & Nutraceutical QC: Certified reference standard for the identification, assay, and standardization of Cistanche deserticolaextracts, herbal formulations, and health products.
- Bone Metabolism Research: Investigation of anti-osteoporotic mechanisms in ovariectomized (OVX) models and osteoblast/osteoclast differentiation studies.
- Inflammation & Neuroprotection: Study of anti-neuroinflammatory effects and mechanisms in neurodegenerative disease models (e.g., Alzheimer's).
Pharmaceutical Analysis: System suitability standard for HPLC, LC-MS, and UPLC analysis of phenylethanoid glycosides.
3.CLINICAL EFFICACY OF PRODUCT
While direct human clinical trials on isolated Cistanoside A are limited, its efficacy is strongly supported by extensive preclinical data. In OVX mouse models, oral administration (20–80 mg/kg) effectively improved bone mineral density, microstructure, and biomechanical strength, comparable to estrogen therapy. In macrophage models, it potently suppresses LPS-induced NO overproduction. Its research "efficacy" is defined by its reliable performance as a high-purity marker compound and its reproducible bioactivity in validating the pharmacological quality of Cistancheresources.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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