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Chemicals
Wilfortrine CAS NO.37239-48-8
<p>Wilfortrine is a naturally derived alkaloid compound renowned for its potent anti-tumor and cytotoxic properties, making it a valuable tool in oncology and cancer biology research. Its unique chemical structure enables targeted disruption of cancer cell proliferation and induction of apoptosis, offering researchers a reliable agent for studying tumor suppression mechanisms and drug resistance. With high purity an…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Wilfortrine |
| CAS NO. | 37239-48-8 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₄₁H₄₇NO₂₀ |
| Molecular Weight | 873.81g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water and dilute acids; partially soluble in DMSO; insoluble in non-polar solvents |
| Endotoxin | ≤ 0.1 EU/mg (for research-grade materials; subject to batch-specific Certificate of Analysis) |
| Biological Activity | Potent anti-tumor and anti-proliferative agent; exhibits cytotoxic effects on various cancer cell lines; modulates cell cycle progression and apoptosis pathways |
| Storage Conditions | Lyophilized powder: Store at -20°C in a dry, dark place; stable for 24–36 months. Reconstituted solutions: Store at -20°C, protected from light, and use within 1–2 weeks; avoid freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Wilfortrine exerts its biological effects by interfering with key cellular signaling pathways involved in cell cycle regulation and apoptosis. It selectively targets rapidly dividing cells, inducing G1/S phase arrest and activating intrinsic apoptotic cascades through mitochondrial membrane depolarization and caspase activation. Additionally, it may modulate oxidative stress responses and inhibit angiogenesis-related pathways, contributing to its broad-spectrum anti-tumor activity. Its mechanism is distinct from conventional chemotherapeutics, offering potential for combination therapy research and mechanistic studies in cancer pharmacodynamics.
2.PRODUCT INDICATIONS
Wilfortrine is primarily indicated for research use in oncology, pharmacology, and cell biology laboratories studying cancer cell behavior, drug screening, and mechanistic toxicology. It is suitable for applications involving tumor cell line cytotoxicity assays, apoptosis induction studies, and investigations into cell cycle regulation. Researchers exploring natural product-derived anti-cancer agents, novel drug leads, or molecular targets in cancer progression will find Wilfortrine a highly relevant and effective compound for their experimental designs.
3.CLINICAL EFFICACY OF PRODUCT
While Wilfortrine has not been approved for clinical use in humans, preclinical studies demonstrate significant efficacy in reducing tumor growth across multiple cancer models, including breast, lung, and colon carcinomas. Its ability to induce apoptosis and inhibit proliferation with relatively low cytotoxicity to normal cells highlights its therapeutic potential. Ongoing research continues to evaluate its pharmacokinetics, toxicity profiles, and synergistic effects with existing chemotherapeutics, positioning Wilfortrine as a promising candidate for future translational medicine and clinical development
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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