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Chemicals
Punicalin CAS NO.65995-64-4
<p>Punicalin is a high-purity hydrolyzable tannin (ellagitannin) primarily extracted from pomegranate peel and Terminalia catappaleaves, widely used as a premium botanical reference standard and active ingredient in nutraceutical R&D. It is characterized by its potent free radical scavenging capacity and multi-target biological activity, making it a key compound for researchers and manufacturers focusing on natural …
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Punicalin |
| CAS NO. | 65995-64-4 |
| Appearance | Off-white to light brown amorphous powder |
| Molecular Formula | C34H22O22 |
| Molecular Weight | 782.52 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in methanol, DMSO, ethanol; slightly soluble in water |
| Endotoxin | ≤ 5 EU/mg (or Not detected, as per batch testing) |
| Biological Activity | Antioxidant, anti-inflammatory, anti-viral, carbonic anhydrase inhibition |
| Storage Conditions | Store at 2–8°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The compound exerts its effects through a multi-pathway approach: it functions as a powerful antioxidant by directly scavenging free radicals and modulating oxidative stress markers (e.g., MDA, GSH-Px), while its anti-inflammatory action is mediated via inhibition of the cGAS-STING signaling pathway and downregulation of pro-inflammatory cytokines (TNF-α, IL-6, iNOS). Additionally, Punicalin exhibits specific enzyme inhibitory activity against carbonic anhydrase and HIV-1 reverse transcriptase, and has been shown to interfere with viral entry mechanisms (e.g., SARS-CoV-2 Spike-ACE2 interaction), underpinning its broad-spectrum bioactivity profile.
2.PRODUCT INDICATIONS
This ingredient is primarily indicated for use in dietary supplements targeting oxidative stress management, liver health support, and anti-aging formulations. In pharmaceutical research, it serves as a lead compound for investigating hepatitis B (HBV) and other viral infections, as well as neuroinflammatory conditions like age-related cognitive decline. It is particularly relevant for R&D teams developing natural alternatives for metabolic syndrome, skincare antioxidants, and gut health products derived from pomegranate extracts.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies demonstrate that Punicalin significantly reduces carrageenan-induced paw edema and protects against CCl4-induced hepatotoxicity by lowering serum transaminase levels. In models of brain aging, it improves cognitive function and synaptic plasticity by mitigating neuroinflammation and oxidative damage. Although human clinical data is still emerging, its efficacy is strongly supported by its high correlation with the known benefits of standardized pomegranate extracts, confirming its role as a validated marker for quality control and bioactivity in natural health products.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Punicalin #CAS65995644 #Ellagitannin #PomegranateExtract #Antioxidant #AntiInflammatory #HBVResearch #Neuroprotection #ResearchChemical #NaturalProduct
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