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Chemicals
naringenin-7-O-β-D-glucoside CAS NO.529-55-5
<p>Naringenin-7-O-β-D-glucoside (Prunin) is a naturally occurring flavonoid glycoside predominantly found in citrus fruits, recognized for its superior water solubility and bioavailability compared to its aglycone form. This high-purity botanical compound is extensively utilized in the nutraceutical and cosmetic industries for its potent antioxidant and anti-inflammatory properties, making it an ideal ingredient for…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | naringenin-7-O-β-D-glucoside |
| CAS NO. | 529-55-5 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C21H22O10 |
| Molecular Weight | 434.39 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water, methanol, ethanol; slightly soluble in DMSO |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Antioxidant, PTP1B inhibitor, improves insulin sensitivity |
| Storage Conditions | Store at 2–8°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The primary mechanism of Naringenin-7-O-β-D-glucoside involves the modulation of key enzymatic and signaling pathways. It functions as a strong inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B), an enzyme implicated in insulin resistance, thereby enhancing insulin sensitivity and glucose uptake. Additionally, it activates the PI3K/Akt pathway and PPARγ, promoting adipocyte differentiation and lipid metabolism. Its antioxidant action is mediated through the scavenging of free radicals and inhibition of nitration processes, while its anti-inflammatory effects are achieved via suppression of LPS-induced NO production.
2.PRODUCT INDICATIONS
This product is indicated for use in formulating functional foods and dietary supplements aimed at supporting glycemic control and managing type 2 diabetes. It is also widely incorporated into anti-aging and protective skincare products, such as serums and creams, to combat environmental damage. Furthermore, it serves as a critical reference standard and active ingredient in pharmaceutical research for metabolic syndrome, cardiovascular health, and anti-inflammatory drug development.
3.CLINICAL EFFICACY OF PRODUCT
Research demonstrates that Naringenin-7-O-β-D-glucoside effectively improves glucose homeostasis by significantly reducing PTP1B expression in insulin-resistant cells, leading to enhanced glucose uptake. In dermatological applications, its potent free radical scavenging capacity provides measurable protection against UV-induced skin damage and oxidative stress. Studies also confirm its ability to favorably modulate lipid accumulation and adiponectin secretion, underscoring its potential in managing obesity-related metabolic disorders with a favorable safety profile.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Naringenin7OGlucoside #Prunin #CitrusFlavonoid #Antioxidant #AntiAging #PTP1BInhibitor #NaturalExtract #CosmeticIngredient
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Global Technology Co., Ltd.
