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Chemicals
Platycodin D3 CAS NO.67884-03-1
<p>Platycodin D3 is a high-purity triterpenoid saponin standard extracted from the root of <em>Platycodon grandiflorum</em>, primarily used as a reference standard in pharmaceutical analysis and natural product research. This product is characterized by its high-performance liquid chromatography (HPLC) purity of ≥98%, supplied as a stable white to off-white crystalline powder for precise quantification and quality c…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Platycodin D3 |
| CAS NO. | 67884-03-1 |
| Appearance | White to off - white crystalline powder |
| Molecular Formula | C63H102O33 |
| Molecular Weight | 1387.46 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in methanol, DMSO; slightly soluble in water; insoluble in n - hexane |
| Endotoxin | ≤0.5 EU/mL |
| Biological Activity | Exhibits anti - inflammatory, immunomodulatory, and potential antiviral activities (in vitro and in vivo studies support its role in regulating immune responses and suppressing inflammatory cytokine production) |
| Storage Conditions | Store at 2 - 8°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Platycodin D3 exerts its pharmacological effects by modulating key signaling pathways involved in inflammation and viral replication. Its mechanism includes the inhibition of the NF-κB signaling pathway, which reduces the expression of pro-inflammatory cytokines and mediators, thereby alleviating inflammatory responses. Additionally, it demonstrates specific anti-HCV (Hepatitis C Virus) activity by targeting the NS5B RNA-dependent RNA polymerase, effectively suppressing viral replication. The compound also exhibits immunomodulatory properties by enhancing mitogen-induced splenocyte proliferation and regulating both Th1 and Th2 cytokine production.
2.PRODUCT INDICATIONS
As a research-grade chemical, Platycodin D3 is indicated for in vitro and in vivo studies focusing on respiratory health, anti-viral therapy, and immunology. It is widely applied in experimental models of asthma, chronic obstructive pulmonary disease (COPD), and airway inflammation due to its ability to reduce airway mucin secretion and alleviate cough symptoms. Furthermore, its anti-HCV activity makes it a candidate for anti-viral drug discovery research, while its immunomodulatory and anti-inflammatory properties support its use in metabolic and neuroprotective studies.
3.CLINICAL EFFICACY OF PRODUCT
In pre-clinical research models, Platycodin D3 has demonstrated significant efficacy in improving lung function and reducing airway remodeling in ovalbumin (OVA)-induced asthmatic mice, comparable to the effects of dexamethasone. Studies show it effectively lowers airway resistance and inflammatory cell infiltration while modulating cytokine levels. In the context of infectious diseases, it inhibits HCV replication in cell-based assays, showing potential as a lead compound for combination therapy with interferon-alpha. Its broad-spectrum anti-inflammatory and antioxidant activities further underscore its therapeutic potential in managing inflammatory and oxidative stress-related conditions.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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