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Chemicals
(±)-Pinocembrin CAS NO.68745-38-0
<p>(±)-Pinocembrin is a high-purity natural flavonoid reference standard primarily used for scientific research and pharmaceutical development. Sourced from natural origins such as propolis and honey, this product is characterized by its high-performance liquid chromatography (HPLC) purity of ≥98%, ensuring reliable and reproducible results in analytical and bioassay applications. It is particularly valued in the st…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | (±)-Pinocembrin |
| CAS NO. | 68745-38-0 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C15H12O4 |
| Molecular Weight | 256.25 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO, methanol, ethanol; slightly soluble in water |
| Endotoxin | ≤10 EU/mg |
| Biological Activity | Potent antioxidant and anti-inflammatory activity; modulates Nrf2 pathway |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The Mechanism of Action of (±)-Pinocembrin centers on its dual capacity to modulate oxidative stress and inflammatory pathways. It functions as a potent activator of the Nrf2 signaling cascade, which upregulates endogenous antioxidant defenses like HO-1 and NQO1, thereby reducing reactive oxygen species (ROS) damage. Concurrently, it inhibits key pro-inflammatory pathways, including NF-κB, MAPK, and NLRP3 inflammasome activation, which leads to decreased production of cytokines such as TNF-α and IL-1β, providing a mechanistic basis for its cell-protective effects in neurological and vascular models.
2.PRODUCT INDICATIONS
Product Indications for (±)-Pinocembrin highlight its primary utility in preclinical research targeting neurological and vascular health. It is extensively applied in studies related to ischemic stroke, cerebral ischemia-reperfusion injury, and neurodegenerative conditions, where its ability to cross the blood-brain barrier is crucial. Additionally, it is indicated for research into cardiovascular protection, including atherosclerosis and endothelial cell injury, as well as general investigations into anti-inflammatory and antioxidant mechanisms, serving academic, pharmaceutical, and biotech R&D sectors.
3.CLINICAL EFFICACY OF PRODUCT
Clinical Efficacy of Product is supported by robust preclinical data and ongoing clinical trials, underscoring its potential as a neuroprotective agent. Research demonstrates its efficacy in improving neurological function and reducing infarct volume in stroke models, with evidence of anti-apoptotic and anti-inflammatory effects. The compound has advanced to Phase II clinical trials in China for ischemic stroke, confirming its translational potential and establishing it as a promising candidate for neurological drug development.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags:Pinocembrin, Flavonoid, Natural Product, Neuroprotective, Anti-inflammatory, Antioxidant, Research Chemical, Pharmaceutical Intermediate, Propolis Extract, Standard Compound, Supplier, Manufacturer, Bulk order, Pharmaceutical.
If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553
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