Beta-D-Fructose 6 phosphate (β-D-F6P) CAS NO. 26177-86-6
<p>Beta-D-Fructose 6-phosphate (β-D-F6P, CAS 26177-86-6) is a high-purity biochemical reagent supplied as a stable disodium salt. It is a central intermediate metabolite in the glycolytic pathway, positioned between Glucose-6-phosphate and Fructose-1,6-bisphosphate. This compound is essential for research in energy metabolism, enzyme kinetics, and metabolic flux analysis, serving as a critical substrate for phosphof…
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Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | β‑D‑Fructose 6‑phosphate (β‑D‑F6P) |
| CAS NO. | 26177‑86‑6 |
| Appearance | White to off‑white crystalline powder |
| Molecular Formula | C₆H₁₃O₉P |
| Molecular Weight | 259.97 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Highly soluble in water (≥100 mg/mL); slightly soluble in methanol, insoluble in ethanol |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Key intermediate in glycolysis/gluconeogenesis; substrate for phosphofructokinase and other carbohydrate metabolism enzymes |
| Storage Conditions | −20 °C (long‑term), sealed, dry, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
β-D-Fructose 6-phosphate acts as a pivotal metabolic substrate and regulatory node. In glycolysis, it is rapidly phosphorylated by PFK-1 to Fructose-1,6-bisphosphate, which is the committed and rate-limiting step of the pathway. It also serves as a precursor in the Pentose Phosphate Pathway and is a key allosteric regulator, influencing the activity of enzymes like PFK-2/FBPase-2 to control the levels of the potent regulator Fructose-2,6-bisphosphate, thereby determining whether cells undergo glycolysis or gluconeogenesis.

2.PRODUCT INDICATIONS
- Enzyme Assays: Substrate for phosphofructokinase (PFK), phosphoglucose isomerase (PGI), and transaldolase.
- Metabolic Studies: Tracer and intermediate for investigating glycolysis, gluconeogenesis, and the Warburg effect in cancer cells.
- Biochemical Reagent: Standard for quality control in diagnostic kits and metabolic pathway reconstitution.
- Cell Metabolism: Component of cell culture media supplements and in vitro energy metabolism studies.
3.CLINICAL EFFICACY OF PRODUCT
As an endogenous metabolite, β-D-F6P itself is not a therapeutic drug. Its "efficacy" in research contexts is demonstrated through its fundamental role in cellular bioenergetics. Preclinical studies utilize it to model metabolic disorders (e.g., diabetes, cancer) by modulating glycolytic flux. Elevated F6P levels are often associated with insulin resistance and hepatic glucose output, making it a valuable biomarker and research tool for understanding metabolic diseases and developing interventions that target glucose metabolism.

4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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