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Chemicals
Tetrahydrocucumin CAS NO. 36062-04-1
<p>Tetrahydrocurcumin (THC) is a premium, colorless hydrogenated metabolite of curcumin derived from turmeric. Unlike its parent compound, it offers superior stability, enhanced bioavailability, and a non-staining white appearance, making it a highly versatile active ingredient for high-performance skincare, nutraceutical, and pharmaceutical formulations. It is particularly valued for delivering the proven benefits …
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Tetrahydrocucumin |
| CAS NO. | 36062-04-1 |
| Appearance | White to off-white powder |
| Molecular Formula | C₂₁H₂₄O₆ |
| Molecular Weight | 372.41 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO (~74 mg/mL); Soluble in Ethanol (~74 mg/mL); Insoluble in Water |
| Endotoxin | Not applicable |
| Biological Activity | Potent antioxidant, anti-inflammatory, CYP450 inhibitor (CYP2C9, CYP3A4), tyrosinase inhibitor |
| Storage Conditions | Powder: -20°C (stable for 3 years); Solution: Aliquot and store at -80°C or -20°C |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Tetrahydrocurcumin primarily functions as a powerful free radical scavenger and tyrosinase inhibitor. It modulates key cellular signaling pathways, including the downregulation of NF-κB to reduce inflammation and the activation of the Nrf2 pathway to bolster endogenous antioxidant defenses. By specifically inhibiting the enzyme tyrosinase and related proteins (TRP-1/TRP-2), it directly interferes with melanin synthesis at the molecular level, providing a dual mechanism of skin brightening and cytoprotection against oxidative stress.
2.PRODUCT INDICATIONS
This ingredient is ideally indicated for inclusion in advanced skincare products targeting hyperpigmentation, age spots, and uneven skin tone, as well as in anti-aging serums and soothing creams for sensitive or irritated skin. It is also utilized in nutraceutical formulations aimed at supporting liver health, metabolic function, and general wellness. The target audience includes cosmetic formulators seeking natural whitening alternatives to hydroquinone, brands developing "clean" anti-aging solutions, and supplement manufacturers focusing on bioactive natural extracts.
3.CLINICAL EFFICACY OF PRODUCT
Clinical and preclinical studies demonstrate that Tetrahydrocurcumin effectively reduces melanin production, with some data suggesting efficacy comparable to or exceeding that of arbutin and kojic acid in brightening skin tone. Its strong antioxidant profile has shown efficacy in protecting against UV-induced skin damage and oxidative stress in various organ systems. Research also indicates potential benefits in improving lipid profiles, supporting neuroprotection, and mitigating inflammatory responses in models of liver and metabolic disorders.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Tetrahydrocurcumin #THC #TurmericMetabolite #SkinWhitening #Antioxidant #NaturalBrightening #AntiAging #CosmeticIngredient
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85244219157
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Global Technology Co., Ltd.
