Chemicals

Salmon Calcitonin CAS NO.47931-85-1

<p>Salmon Calcitonin is a high-purity peptide hormone drug and raw material used for regulating calcium metabolism and bone resorption. It is indicated for the treatment of postmenopausal osteoporosis, Paget&#39;s disease of bone, and hypercalcemia. Available in injectable and nasal spray formulations, it is characterized by its high receptor affinity, long duration of action, and significant analgesic effect on bon…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Salmon Calcitonin
CAS NO.
47931-85-1
Appearance
White to off-white lyophilized powder
Molecular Formula
C145H240N44O48S2
Molecular Weight
3431.91 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in water; soluble in dilute acetic acid

Endotoxin<0.1 EU/mg
Biological Activity
Equivalent to reference standard 
Storage Conditions
Store at 2–8°C, protected from light; stable for 24 months under recommended conditions
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Salmon Calcitonin exerts its therapeutic effects by specifically binding to calcitonin receptors on osteoclasts, strongly inhibiting their activity and reducing bone resorption. It increases renal excretion of calcium, phosphorus, and sodium, thereby lowering serum calcium levels. Additionally, it acts on the central nervous system to provide analgesic effects, particularly relieving bone pain associated with osteoporosis and Paget's disease. Its mechanism ensures rapid onset and sustained regulation of bone metabolism.

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2.PRODUCT INDICATIONS

This product is primarily indicated for the treatment of postmenopausal osteoporosis in women who cannot tolerate or are contraindicated for estrogen therapy. It is also used for Paget's disease of bone (osteitis deformans), especially in cases where other treatments are ineffective. Furthermore, it is applied in the management of hypercalcemia and hypercalcemic crisis secondary to malignancies, as well as for acute bone loss prevention due to sudden immobilization and neuropathic osteoarthropathy (Sudeck's disease).

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3.CLINICAL EFFICACY OF PRODUCT

Clinical studies, such as the PROOF study, have demonstrated that intranasal Salmon Calcitonin (200 IU/day) can significantly reduce the risk of new vertebral fractures by approximately 33% in postmenopausal women with osteoporosis. It effectively increases lumbar spine bone mineral density (BMD) by 1–1.5% and provides rapid relief from bone pain. In Paget's disease, it significantly reduces bone turnover markers (alkaline phosphatase and urinary hydroxyproline). The nasal spray formulation offers comparable efficacy to injections with improved convenience and tolerability.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553