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Chemicals
Fisetin CAS NO.528-48-3
<p>Fisetin is a potent natural senolytic flavonoid extracted from strawberries, apples, and the smoke tree (<em>Cotinus coggygria</em>). This high-purity supplement is specifically formulated to target cellular aging by clearing senescent "zombie cells," reducing chronic inflammation, and protecting neurological function. It is designed for health-conscious adults seeking to support longevity, cognitive clarity, and…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Fisetin |
| CAS NO. | 528-48-3 |
| Appearance | Yellow to orange crystalline powder |
| Molecular Formula | C15H10O6 |
| Molecular Weight | 286.24 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO, ethanol, and slightly soluble in water; insoluble in non - polar organic solvents like hexane |
| Endotoxin | ≤0.5 EU/mg |
| Biological Activity | Exhibits senolytic activity by selectively eliminating senescent cells, activates Nrf2 pathway to enhance antioxidant defense, modulates sirtuin (SIRT1) activity to regulate cellular metabolism and aging - related processes, and has anti - inflammatory effects by inhibiting NF - κB signaling |
| Storage Conditions | Store in a cool, dry place at 2 - 8°C, protected from light and moisture; avoid long - term exposure to air |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Fisetin works primarily as a senolytic agent by selectively inducing apoptosis in senescent cells—dysfunctional cells that accumulate with age and contribute to tissue decline—while sparing healthy ones. It modulates key longevity pathways including SIRT1 activation and mTOR inhibition, while also functioning as a powerful Nrf2 activator to boost endogenous antioxidant defenses and mitigate oxidative stress at the cellular level.
2.PRODUCT INDICATIONS
This product is indicated for individuals targeting age-related cellular decline, including those seeking to reduce frailty, support joint health, and maintain skin elasticity. It is also aimed at users focusing on brain health, particularly for memory support and neuroprotection against cognitive decline, as well as those managing metabolic wellness through natural anti-inflammatory and antioxidant support without pharmaceutical interventions.
3.CLINICAL EFFICACY OF PRODUCT
Human clinical trials, such as the FISET-AGE study, demonstrate that Fisetin supplementation significantly reduces biomarkers of cellular senescence and inflammation, with data showing improved physical function and walking speed in older adults. Early-phase trials in neuroprotection report enhancements in cognitive scores, supported by preclinical evidence of lifespan extension and robust senolytic activity that clears a majority of senescent cells in model organisms.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags:Fisetin, Senolytic, AntiAging, Longevity, CellularHealth, BrainHealth, Flavonoid, NAD, Sirt1, Nrf2, ZombieCells, Healthspan, LifeExtension, NaturalSupplement, CognitiveFunction, Supplier, Manufacturer, Bulk order, Pharmaceutical.
If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553
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Global Technology Co., Ltd.
