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Chemicals
Palmitoyl Tripeptide-3/5 CAS NO.623172-56-5
<p>Palmitoyl Tripeptide-3/5 (CAS NO. 623172-56-5) is a synthetic, lipopeptide cosmetic ingredient composed of a tripeptide sequence conjugated to a palmitoyl fatty acid chain. This modification enhances skin penetration and stability. It is designed as a biomimetic signaling peptide that mimics natural collagen fragments to promote the synthesis of key extracellular matrix (ECM) components, effectively targeting wri…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Palmitoyl Tripeptide - 3/5 |
| CAS NO. | 623172-56-5 |
| Appearance | White to off-white powder |
| Molecular Formula | C₃₃H₆₅N₅O₅ |
| Molecular Weight | 611.90 g/mol |
| Amino Acid Sequence | Palmitoyl-Lys-Val-Lys-OH (Pal-KVK-OH) |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMF (30 mg/mL), DMSO (30 mg/mL), ethanol (30 mg/mL); slightly soluble in water (solubilize with organic solvent first); water-soluble solution available. |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Lipopeptide mimicking TGF-β signaling; activates thrombospondin-1 to stimulate collagen I/III synthesis, enhances skin firmness, reduces wrinkles (23% reduction with 2% active over 2 months); improves skin elasticity and hydration. |
| Storage Conditions | Store at 2–8°C for short-term (6 months); -20°C for long-term (2+ years) in a dry, light-protected container. Avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Palmitoyl Tripeptide-3/5 acts primarily as a signal peptide. It is designed to mimic specific amino acid sequences present in the structure of endogenous collagen and other ECM proteins. Upon penetration into the dermis, it binds to receptors on the surface of fibroblasts, the primary cells responsible for producing skin's supportive structure. This binding stimulates a signaling cascade that upregulates the fibroblasts' activity, leading to increased production of collagen (types I and III), elastin, fibronectin, and glycosaminoglycans (GAGs). This process helps to rebuild and repair the dermal matrix, restoring skin density and elasticity.
2.PRODUCT INDICATIONS
This product is indicated for cosmetic science and the formulation of anti-aging skincare products. Key applications include: as an active ingredient in serums, creams, and lotions designed to reduce the appearance of fine lines and wrinkles; in formulations targeting loss of skin firmness and elasticity; for improving overall skin texture and density; and as part of comprehensive anti-aging regimens aimed at combating chronological aging and photoaging by stimulating the skin's natural repair mechanisms.
3.CLINICAL EFFICACY OF PRODUCT
Palmitoyl Tripeptide-3/5 is supported by in vitro data demonstrating its stimulatory effect on fibroblast activity and ECM protein synthesis. Clinical studies on cosmetic formulations containing this peptide have shown measurable efficacy in improving signs of skin aging. Typical results include a visible reduction in wrinkle depth and volume, improved skin elasticity and firmness, and enhanced skin smoothness. Regular application contributes to a more youthful and rejuvenated skin appearance, validating its role as an effective bioactive ingredient for anti-aging skincare.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Pentapeptide-25, Anti-aging peptide, Collagen booster, Skin firming, Wrinkle reducer, Cosmetic ingredient, Peptide synthesis, Skincare, CAS 1000313-64-36, Synthetic peptide, Dermal repair, Extracellular matrix, Fibroblast activation, Topical serum, Cosmetic research, High purity peptide, Supplier, Manufacturer, Bulk order, Cosmetic raw materialResearch peptide, Pharmaceutical
If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510
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Global Technology Co., Ltd.
