Chemicals

Pentapeptide-18 CAS NO.64963-01-5

<p>Pentapeptide-18 is a synthetic, biomimetic pentapeptide specifically engineered for cosmetic and topical dermatological applications. This advanced peptide is designed to target and improve the appearance of dark under-eye circles by addressing the vascular and pigmentation components that contribute to this common concern, promoting a brighter and more refreshed eye contour.<br/></p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Pentapeptide-18
CAS NO.
64963-01-5
Appearance
White to off-white lyophilized powder
Molecular Formula
  C29H39N507
Molecular Weight
569.658g/mol
Purity (RP-HPLC)
≥ 95%
Solubility

Soluble in water, ethanol, and common cosmetic solvents 

Endotoxin< 1.0 EU/mg (if for research/injectable grade)
Biological Activity
Cosmetic neuropeptide; typically exhibits anti-wrinkle or neuromodulating activity.
Storage Conditions
Store at -20°C, protected from light and moisture. After reconstitution, store at 2-8°C.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Pentapeptide-18 works through a dual-action vasoprotective and depigmenting mechanism:

  1. Vasoprotection: It helps to strengthen capillary walls and reduce their permeability in the delicate under-eye area. This minimizes the leakage of red blood cells (RBCs) into the surrounding tissue.

  2. Anti-Pigmentation: Following RBC extravasation, hemoglobin breaks down into hemosiderin, which can deposit and cause a bluish or brownish discoloration. Pentapeptide-18 is designed to inhibit the activity of heme oxygenase-1, a key enzyme involved in this breakdown process, thereby reducing the formation of pigmentary deposits.

2.PRODUCT INDICATIONS

This product is indicated for cosmetic science research and the formulation of targeted eye care treatments. Key applications include: as a primary active ingredient in serums, creams, and gels specifically designed to reduce the appearance of dark under-eye circles and periorbital hyperpigmentation; in products aimed at improving the overall luminosity and homogeneity of the eye contour area; and for use in cosmeceuticals targeting vascular fragility and pigment-related discoloration in sensitive skin zones.

3.CLINICAL EFFICACY OF PRODUCT

Pentapeptide-18 is a cosmetic bioactive ingredient. Its efficacy is supported by in vitro data demonstrating its action on capillary integrity and pigmentary pathways. Clinical studies on finished formulations containing this peptide typically show a significant reduction in the color intensity and surface area of dark circles, leading to a visibly brighter, more rested, and uniform under-eye appearance. Regular use contributes to an overall reduction in the signs of fatigue and a more rejuvenated look, validating its role as a specialized solution for this specific aesthetic concern.

  • 4.Certificate

  • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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