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Chemicals
Lanosterol CAS NO.79-63-0
<p>Lanosterol is a key tetracyclic triterpenoid and the first committed sterol intermediate in the cholesterol biosynthesis pathway. It is biosynthesized from squalene-2,3-epoxide via enzymatic cyclization. As a central precursor, Lanosterol is essential for the production of all animal and fungal sterols, including cholesterol, steroid hormones, and vitamin D. It is primarily recognized for its critical role in cel…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Lanosterol |
| CAS NO. | 79-63-0 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C₃₀H₅₀O |
| Molecular Weight | 426.72 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Practically insoluble in water; soluble in chloroform, ether, ethanol, and other organic solvents (e.g., DMSO, methanol) |
| Endotoxin | <0.1 EU/mg |
| Biological Activity | Key intermediate in cholesterol biosynthesis; precursor to all animal steroids; studied for potential anti-cataract and anti-inflammatory effects in preclinical research. |
| Storage Conditions | Sealed container, stored at 2–8°C (refrigerated), protected from light, moisture, and air; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 10g |
1.MECHANISM OF ACTION
- In biosynthesis, Lanosterol undergoes a series of demethylation, reduction, and isomerization reactions catalyzed by enzymes (e.g., CYP51A1) to form cholesterol. Beyond its precursor function, Lanosterol has been identified as a potent agent in reversing protein aggregation. Research indicates it can bind to and solubilize misfolded proteins, such as crystallins in the eye lens, thereby reducing cataract formation. Its action involves penetrating cell membranes and directly interacting with aggregated proteins to promote their disaggregation.
2.PRODUCT INDICATIONS
Lanosterol is indicated for use as a high-value intermediate in the synthesis of steroid drugs (e.g., hormones, corticosteroids) and vitamin D analogs. In ophthalmic research and formulation, it is used in studies and products targeting cataract prevention and treatment. Additionally, it finds application in cosmetic and skincare products for its potential anti-aging and cell membrane-stabilizing properties, as well as in biochemical research as a standard or substrate for enzyme studies.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
3.CLINICAL EFFICACY OF PRODUCT
In vitro and in vivo studies, particularly on lens organ cultures and animal models, have demonstrated Lanosterol's efficacy in significantly reducing the size and opacity of protein aggregates associated with cataracts. Clinical research is ongoing, with preliminary evidence supporting its potential as a therapeutic agent for age-related and congenital cataracts, potentially offering a non-surgical intervention. Its role in maintaining lens transparency and cellular homeostasis underscores its therapeutic promise in ophthalmology.
4.Certificate
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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Global Technology Co., Ltd.
