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Chemicals
Wedelolactone CAS NO.524-12-9
<p>Wedelolactone is a naturally occurring coumestan compound primarily extracted from medicinal herbs such as <em>Eclipta prostrata</em>and <em>Wedelia calendulacea</em>, renowned for its potent anti-inflammatory and hepatoprotective properties. It serves as a high-value bioactive molecule in the pharmaceutical, nutraceutical, and cosmetic research fields. This versatile ingredient is essential for formulating advan…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Wedelolactone |
| CAS NO. | 524-12-9 |
| Appearance | Yellow to yellow - brown crystalline powder |
| Molecular Formula | C₁₆H₁₀O₇ |
| Molecular Weight | 314.25 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO, slightly soluble in ethanol, insoluble in water |
| Endotoxin | ≤10 EU/mg (for biological activity testing) |
| Biological Activity | Anti - inflammatory, antioxidant, inhibits NF - κB pathway, anti - tumor activity |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The mechanism of action of Wedelolactone primarily involves the inhibition of key inflammatory signaling pathways, notably the NF-κB pathway, thereby suppressing the production of pro-inflammatory cytokines and mediators. It also functions as a strong antioxidant, scavenging free radicals and mitigating oxidative stress-induced cellular damage. Additionally, it exhibits anti-fibrotic activity by modulating TGF-β signaling and demonstrates potential anti-tumor effects through the induction of apoptosis and inhibition of cancer cell proliferation, contributing to its broad therapeutic profile.
2.PRODUCT INDICATIONS
This product is specifically indicated for use in dietary supplements and herbal formulations aimed at supporting liver detoxification, reducing inflammation, and managing conditions like hepatitis and liver fibrosis for individuals with hepatic concerns. It is also suitable for application in cosmeceuticals targeting inflammatory skin disorders such as acne and eczema, as well as for research in oncology, immunology, and metabolic diseases. This makes Wedelolactone a valuable component for both therapeutic health products and biomedical studies.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical and emerging clinical studies substantiate the efficacy of Wedelolactone, demonstrating its hepatoprotective effects in models of chemical-induced liver injury and its ability to reduce inflammatory markers in autoimmune conditions. Research highlights its anti-proliferative activity against various cancer cell lines and its potential in alleviating skin inflammation. This evidence supports its application in liver health supplements, anti-inflammatory skincare, and as a promising candidate for further development in cancer and inflammatory disease therapeutics.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Wedelolactone, #AntiInflammatory, #LiverHealth, #EcliptaProstrata, #NFkBInhibitor, #NaturalCompound, #Hepatoprotective, #SkinCare, #CancerResearch, #HerbalExtract
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85296236544
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Global Technology Co., Ltd.
