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Chemicals
Tetrandrine CAS NO.518-34-3
<p>Tetrandrine is a naturally derived bisbenzylisoquinoline alkaloid primarily extracted from the root of the medicinal plant <em>Stephania tetrandra</em>. Renowned for its broad spectrum of pharmacological activities, it is a high-value active compound in the nutraceutical, research, and pharmaceutical development sectors. This multi-functional ingredient is pivotal for developing advanced formulas aimed at address…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Tetrandrine |
| CAS NO. | 518-34-3 |
| Appearance | White to off - white crystalline powder |
| Molecular Formula | C38H42N2O6 |
| Molecular Weight | 622.75 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO |
| Endotoxin | ≤0.1 EU/mg (or "Not tested" if not applicable) |
| Biological Activity | Anti - inflammatory, anti - fibrotic, calcium channel blocking |
| Storage Conditions | Store at 2–8°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The primary mechanism of action of Tetrandrine involves functioning as a potent calcium channel blocker, modulating intracellular calcium ion influx and thereby influencing a variety of cellular processes. It also exerts significant anti-inflammatory and anti-fibrotic effects by inhibiting critical signaling pathways, such as the NF-κB pathway, and by suppressing the activity of pro-inflammatory cytokines and fibrogenic factors. Additionally, it has been shown to induce apoptosis in certain cell types and exhibit anti-angiogenic properties, contributing to its multifaceted therapeutic profile.
2.PRODUCT INDICATIONS
This product is indicated for application in research and development focused on inflammatory disorders, fibrotic diseases, and cardiovascular conditions. It serves as a key compound for scientists investigating pulmonary fibrosis, rheumatoid arthritis, hypertension, and certain types of cancer. Furthermore, as a potent herbal derivative, it is utilized in the development of specialized nutraceuticals targeting chronic inflammation and immune modulation, making it a valuable resource for both academic research and commercial product innovation.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies and initial clinical data support the therapeutic potential of Tetrandrine, with research demonstrating its efficacy in reducing inflammation and fibrosis in models of liver and lung disease. Investigations highlight its potential to lower blood pressure and exhibit anti-tumor activity in various cell lines. This body of evidence underpins its application as a promising candidate for drug development and as a basis for advanced therapeutic supplements, particularly for conditions with limited treatment options.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Tetrandrine, #NaturalMedicine, #AntiInflammatory, #AntiFibrotic, #CalciumChannelBlocker, #StephaniaTetrandra, #Bisbenzylisoquinoline, #DrugDiscovery, #HerbalExtract, #ResearchChemical
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