Trilobatin CAS NO.4192-90-9

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

Trilobatin primarily functions by inhibiting the activity of α-glucosidase and α-amylase in the intestine, thereby delaying the hydrolysis and absorption of carbohydrates to reduce postprandial blood glucose spikes. At the cellular level, it activates the AMPK/Nrf2/SIRT3 signaling pathway to enhance mitochondrial function and reduce oxidative stress, while also suppressing the NF-κB signaling pathway to inhibit the release of pro-inflammatory cytokines such as TNF-α and IL-6, providing a multi-target mechanism for metabolic regulation.

2.PRODUCT INDICATIONS

This product is indicated for use as a raw material in the development of functional foods and dietary supplements aimed at managing blood glucose levels, particularly for individuals with pre-diabetes or type 2 diabetes seeking natural sugar alternatives. It is also indicated for research applications in the fields of anti-aging, neuroprotection (e.g., Alzheimer's disease models), and bone health (osteoporosis), targeting research institutions and manufacturers focused on natural product-based therapeutics.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies have demonstrated that Trilobatin significantly improves insulin sensitivity and glucose tolerance in diabetic animal models, effectively lowering fasting blood glucose and HbA1c levels. In models of non-alcoholic fatty liver disease (NAFLD), it has been shown to reduce liver fat accumulation and inflammation. Furthermore, in cognitive impairment models, it exhibits neuroprotective effects by reducing amyloid-beta toxicity and improving memory function, supporting its potential as a multi-functional bioactive compound.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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