Curdione CAS NO.13657-68-6

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

The pharmacological action of Curdione primarily involves the induction of ferroptosis in cancer cells by modulating m6A methylation pathways via METTL14 and YTHDF2, leading to iron ion accumulation and lipid peroxidation. Additionally, it exerts its effects by targeting key proteins such as YTHDF1 and IDO1, which regulate the tumor microenvironment, resulting in cell cycle arrest at the G2/M phase and the activation of both apoptotic and autophagic pathways to suppress tumor growth.

2.PRODUCT INDICATIONS

Curdione is indicated for scientific investigation into the treatment of various malignancies, including colorectal cancer, uterine leiomyomas (fibroids), and uterine leiomyosarcoma. It is also utilized in research related to vascular endothelial protection and atherosclerosis, serving as a critical tool for scientists and clinicians exploring novel therapeutic strategies for solid tumors and inflammatory conditions.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that Curdione significantly reduces tumor volume and weight in xenograft models without inducing significant toxicity to normal organs. It exhibits a concentration-dependent suppression of cell viability and proliferation, effectively ameliorating the dysregulated inflammatory microenvironment and attenuating fibrotic progression, thereby highlighting its potential as a promising candidate for adjuvant cancer therapy.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags:Curdione, Sesquiterpene, Natural Product, Anti-cancer, Anti-inflammatory, Zedoary, Traditional Chinese Medicine, Phytochemical, Research Chemical, Pharmaceutical Standard, HPLC 98%, Curcumae Rhizoma, Ferroptosis, YTHDF1, IDO1, Supplier, Manufacturer, Bulk order,  Pharmaceutical.

If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553