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Chemicals
Metilprednisolone CAS NO.83-43-2
<p><h3></h3></p><div class="ybc-p">Methylprednisolone is a potent synthetic glucocorticoid renowned for its strong anti-inflammatory and immunosuppressive effects. It is approximately five times more potent than hydrocortisone but exhibits minimal mineralocorticoid activity, making it a preferred choice for managing acute and chronic inflammatory conditions without significant fluid-retention side effects. This vers…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Methylprednisolone |
| CAS NO. | 83-43-2 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C₂₂H₃₀O₅ |
| Molecular Weight | 374.47 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in methanol, ethanol, and chloroform; slightly soluble in water; insoluble in ether |
| Endotoxin | < 5 EU/mg (for pharmaceutical grade) |
| Biological Activity | Potent synthetic glucocorticoid with strong anti-inflammatory, immunosuppressive, and anti-allergic effects; used to treat inflammatory and autoimmune disorders, allergic reactions, and certain cancers |
| Storage Conditions | Store at 2–8°C, protected from light and moisture; avoid prolonged exposure to air |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Methylprednisolone exerts its therapeutic effects by binding to intracellular glucocorticoid receptors, which then modulate gene transcription. This process suppresses the production of key pro-inflammatory cytokines (such as IL-6 and TNF-α), inhibits leukocyte migration, and reduces capillary permeability. By stabilizing cell membranes and preventing the release of inflammatory mediators like prostaglandins, it effectively controls the body's inflammatory and immune responses at a molecular level.
2.PRODUCT INDICATIONS
This product is indicated for a wide spectrum of conditions, including rheumatic disorders (e.g., rheumatoid arthritis, lupus), severe allergic reactions, and dermatological diseases like psoriasis. It is also critical in managing endocrine disorders, acute respiratory distress, and neurological conditions such as multiple sclerosis relapses. Additionally, it serves as an immunosuppressant in organ transplantation and is used as replacement therapy for adrenal insufficiency.
3.CLINICAL EFFICACY OF PRODUCT
Clinical evidence confirms that Methylprednisolone significantly improves outcomes in acute spinal cord injury when administered within 8 hours, enhancing short-term motor recovery. In respiratory medicine, it reduces mortality and the need for mechanical ventilation in severe COVID-19 and ARDS patients. For autoimmune disorders like multiple sclerosis, high-dose regimens are proven to accelerate relapse recovery and reduce disability scores.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Methylprednisolone #Medrol #Corticosteroid #AntiInflammatory #Immunosuppressant #Glucocorticoid #RheumatoidArthritis #MultipleSclerosis
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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