Tectochrysin CAS NO.520-28-5

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

Tectochrysin exerts its biological effects primarily through the potent inhibition of key inflammatory and oncogenic signaling pathways. It functions as a direct inhibitor of NF-κB by binding to the p50 subunit, thereby preventing the phosphorylation of IκB and the subsequent nuclear translocation of the p50/p65 heterodimer. Additionally, it demonstrates significant activity against the JAK3/STAT3 pathway, suppressing STAT3 phosphorylation which is crucial for inducing apoptosis in cancer cells and modulating macrophage-mediated inflammation, positioning it as a multi-target agent for complex disease models.

2.PRODUCT INDICATIONS

This product is indicated for in vitro and in vivo research applications targeting a range of pathological conditions, including non-small cell lung cancer (NSCLC), colon cancer, and rheumatoid arthritis. It is also applied in studies investigating diabetic retinopathy, Alzheimer's disease-related cognitive impairment, and oxidative stress-induced cellular damage. The target user base includes academic researchers, pharmaceutical R&D scientists, and biotech companies seeking to validate the therapeutic potential of natural compounds in oncology, immunology, and neurodegenerative disease models.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies have demonstrated that Tectochrysin administration leads to significant tumor growth inhibition in xenograft models, with reductions in tumor volume and weight observed in colon cancer studies. In models of rheumatoid arthritis, it ameliorates bone erosion and synovitis by reducing inflammatory cytokine release from macrophages. Furthermore, in cognitive impairment models, it has been shown to improve spatial memory performance and reduce Aβ accumulation, highlighting its translational potential from bench to bedside for future clinical development in these areas.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags:Tectochrysin, Techtochrysin, Flavonoid, Natural Product, NF-κB Inhibitor, STAT3 Inhibitor, JAK3 Inhibitor, Apoptosis, Anti-cancer, Anti-inflammatory, Alpinia Oxyphylla, Research Chemical, Laboratory Reagent, Signal Transduction, Phytochemical, Supplier, Manufacturer, Bulk order,  Pharmaceutical.

If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553