Calycosin-7-glucoside CAS NO.20633-67-4

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

The compound exerts its therapeutic effects by modulating multiple signaling pathways, including the activation of the PI3K/Akt and Sirt1/FoxO1 axes to promote cell survival and mitigate oxidative stress. It specifically regulates the NO/Caveolin-1/MMPs cascade to protect blood-brain barrier integrity during ischemic events and inhibits the p38/MAPK pathway to suppress inflammatory cytokine release and foam cell formation in macrophages, thereby addressing the core mechanisms of vascular and neuronal damage.

2.PRODUCT INDICATIONS

This product is indicated for use as a critical analytical standard in the quality control of Astragalus-based pharmaceuticals and dietary supplements, ensuring batch-to-batch consistency. For research applications, it is utilized in studies targeting neuroprotection against cerebral ischemia-reperfusion injury, cardioprotection in myocardial infarction models, anti-atherosclerosis by reducing lipid accumulation, and as a potential cosmetic ingredient for its tyrosinase inhibitory activity aimed at skin whitening.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that Calycosin-7-glucoside significantly reduces infarct volume and histological damage in rat models of stroke, improves hemodynamic parameters and reduces oxidative stress markers in myocardial ischemia, and effectively attenuates atherosclerotic plaque formation by inhibiting macrophage foam cell generation. While human clinical trial data is still emerging, its robust in vivo efficacy profile supports its role as a promising lead compound for drug development in ischemic diseases.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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