Image not available
Chemicals
Catalpol CAS NO.2415-24-9
<p>Catalpol is a natural iridoid glycoside primarily extracted from the roots of <em>Rehmannia glutinosa</em>, renowned for its potent neuroprotective, anti-inflammatory, and anti-diabetic properties. This compound effectively combats oxidative stress and neuronal damage, making it a highly valuable candidate for research in neurodegenerative diseases, metabolic disorders, and tissue repair. Its excellent water solu…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
Source categories
About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Catalpol |
| CAS NO. | 2415-24-9 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C15H22O10 |
| Molecular Weight | 362.33 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water, slightly soluble in methanol; insoluble in chloroform and ether |
| Endotoxin | < 5 EU/mg (for pharmaceutical grade) |
| Biological Activity | Potent neuroprotective agent; inhibits oxidative stress, reduces inflammation, and promotes nerve regeneration; exhibits anti-apoptotic and anti-fibrotic effects; used in research for neurodegenerative diseases, diabetes complications, and tissue repair |
| Storage Conditions | Store at 2–8°C, protected from light and moisture; avoid freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Catalpol exerts its therapeutic effects by modulating multiple cellular signaling pathways, including the Nrf2/Keap1 pathway to upregulate antioxidant enzymes like HO-1 and NQO1, thereby reducing oxidative stress. It inhibits inflammation by suppressing the NF-κB pathway and downregulating pro-inflammatory cytokines such as TNF-α and IL-6. Additionally, it promotes neuronal survival and regeneration by activating the PI3K/Akt pathway, inhibiting the MAPK pathway, and reducing apoptosis via the mitochondrial Bcl-2/Bax axis.
2.PRODUCT INDICATIONS
Catalpol is ideally indicated for research in neurodegenerative conditions like Alzheimer's and Parkinson's diseases, where it helps reduce neuroinflammation and cognitive decline. It is also valuable in diabetic research for mitigating complications such as nephropathy and neuropathy. Furthermore, its application extends to cardiovascular studies for protecting against ischemic injury, as well as in dermatology for promoting wound healing and skin repair.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies demonstrate that Catalpol significantly improves learning and memory in Alzheimer's disease models by reducing amyloid-beta accumulation and tau hyperphosphorylation. In diabetic models, it alleviates kidney damage and neuropathy by lowering blood glucose and oxidative stress. Experimental data also confirm its efficacy in reducing cerebral infarct volume after stroke and accelerating skin wound healing, supporting its broad therapeutic potential across multiple disease areas.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Catalpol #IridoidGlycoside #Neuroprotection #AntiInflammatory #Antioxidant #RehmanniaGlutinosa #DiabeticNephropathy #AlzheimersResearch #NaturalProduct #DrugDiscovery
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
More from this supplier
Global Technology Co., Ltd.
