Chemicals

Galangin 3-O-methyl ether CAS NO.6665-74-3

<p>Galangin 3-O-methyl ether, also known as 3-O-Methylgalangin, is a high-purity natural flavonoid compound primarily extracted from the rhizome of Alpinia officinarum (Lesser Galangal). This derivative is characterized by its enhanced lipophilicity and improved cellular permeability compared to its parent compound, making it a superior candidate for research in drug discovery and nutraceutical development. It is su…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Galangin 3-O-methyl ether
CAS NO.
6665-74-3
Appearance
Yellow to light yellow powder
Molecular Formula
C16H12O5
Molecular Weight
284.26 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility

Soluble in DMSO, methanol, ethanol; slightly soluble in water

Endotoxin< 0.1 EU/mg
Biological Activity
Inhibits pancreatic lipase; modulates HDAC2 and PI3K-AKT signaling pathway
Storage Conditions
Store at 2–8°C, protected from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The compound exerts its biological effects through multiple molecular pathways, primarily functioning as a potent inhibitor of pancreatic lipase to reduce fat absorption and as a selective modulator of epigenetic enzymes. It has been shown to directly target Histone Deacetylase 2 (HDAC2), leading to the subsequent inactivation of the PI3K-AKT signaling pathway, which is crucial for regulating cell proliferation and survival. Additionally, its antibacterial activity is attributed to its ability to disrupt microbial membrane integrity and inhibit key bacterial enzymes.

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2.PRODUCT INDICATIONS

This product is indicated for use in scientific research focused on metabolic disorders, cardiovascular health, and infectious diseases. It is particularly relevant for studies investigating anti-obesity agents due to its lipase inhibitory properties, as well as for research on hypertrophic cardiomyopathy and cardiac hypertrophy models. Researchers in microbiology utilize it for its efficacy against Gram-positive bacteria and specific pathogens like Pseudomonas aeruginosa, while oncology researchers explore its anti-proliferative effects on various cancer cell lines.

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3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies in animal models have demonstrated significant clinical efficacy, particularly in mitigating pathological cardiac hypertrophy and improving cardiac function in transgenic mouse models of hypertrophic cardiomyopathy. Administration of Galangin 3-O-methyl ether has been shown to dose-dependently reduce the expression of hypertrophy marker genes and improve echocardiographic parameters. While human clinical data is still emerging, its robust in vivo anti-hypertrophic and hypolipidemic effects position it as a promising lead compound for therapeutic development.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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