kuwanon G CAS NO.75629-19-5

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

Kuwanon G exerts its pharmacological effects primarily by acting as a potent antagonist of the PI3K/AKT/mTOR signaling pathway, thereby inhibiting cancer cell proliferation and inducing apoptosis. It also functions as a cannabinoid CB1 receptor antagonist to suppress appetite, and modulates inflammatory responses by downregulating pro-inflammatory cytokines such as TNF-α and IL-1β, while enhancing antioxidant enzyme activity to protect cellular integrity.

2.PRODUCT INDICATIONS

This product is indicated for use in scientific research focused on anti-tumor studies (particularly for gastric cancer, breast cancer, and liver cancer), anti-obesity and metabolic syndrome investigations, and neuroprotective applications against conditions like diabetic encephalopathy and ischemic stroke. It is suitable for researchers in pharmacology, oncology, and natural product chemistry who require a high-purity standard for in vitro and in vivo mechanistic studies.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that Kuwanon G significantly inhibits tumor growth and metastasis in xenograft models, reduces food intake and body weight in diet-induced obese mice, and ameliorates cognitive impairment and blood-brain barrier disruption in models of diabetic encephalopathy and cerebral ischemia. These robust in vivo data support its potential as a lead compound for developing novel therapeutics, although human clinical trials are still pending.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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