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Chemicals
Pimaric acid CAS NO.33464-71-0
<p>Pimaric acid is a natural diterpenoid resin acid primarily sourced from pine trees and select medicinal plants like <em>Aralia cordata</em>. It is widely utilized in pharmacological research due to its notable anti-inflammatory, antimicrobial, and anticancer properties. This compound is particularly valuable for studying cellular mechanisms related to oxidative stress and tumor progression, making it a key ingred…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Pimaric Acid |
| CAS NO. | 127-27-5 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C₂₀H₃₀O₂ |
| Molecular Weight | 302.45 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO, methanol, ethanol, chloroform; slightly soluble in water |
| Endotoxin | < 10 EU/mg (if applicable for pharmaceutical grade) |
| Biological Activity | Naturally occurring diterpenoid found in conifers; exhibits anti-inflammatory, antimicrobial, and potential anticancer activities |
| Storage Conditions | Store at 2–8°C, dry, protected from light, tightly sealed |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The compound exerts its effects by modulating critical cellular signaling pathways. It significantly inhibits the activation of NF-κB and AP-1 transcription factors, leading to the downregulation of matrix metalloproteinase-9 (MMP-9), which is crucial for reducing inflammation and preventing tumor metastasis. Additionally, Pimaric acid induces apoptosis and cell cycle arrest in cancer cells by triggering endoplasmic reticulum stress and activating caspase cascades. Its antimicrobial action is attributed to the disruption of bacterial cytoplasmic membranes and the effective inhibition of biofilm formation.
2.PRODUCT INDICATIONS
This product is intended for research applications in pharmacology and biochemistry, specifically for investigating inflammatory disorders, cardiovascular diseases, and cancer biology. It is also suitable for developing antimicrobial agents, particularly for oral care products aimed at combating biofilm-forming pathogens like Streptococcus mutans. Furthermore, it serves as a promising candidate for formulating natural preservatives and functional ingredients in the cosmetic and nutraceutical industries.
3.Clinical Efficacy of Product
Preclinical studies demonstrate that Pimaric acid effectively suppresses TNF-α-induced MMP-9 production and smooth muscle cell migration, indicating strong potential in managing vascular inflammation and atherosclerosis. In cancer models, it has shown selective cytotoxicity against ovarian cancer cells, inhibiting proliferation and metastasis. Antimicrobial assays confirm its potency against oral pathogens, with significant reductions in biofilm formation and acid production, supporting its efficacy as a therapeutic agent in experimental settings.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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