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Chemicals
Asperulosidic acid CAS NO.25368-11-0
<p><strong>Asperulosidic Acid</strong> (CAS NO. 25368-11-0) is a high-purity, naturally occurring <strong>iridoid glucoside</strong> isolated from various medicinal plants, particularly those in the Rubiaceae family, such as <em>Morinda citrifolia</em>(Noni) and <em>Gardenia jasminoides</em>. It is a <strong>monoterpene-derived glycoside</strong> and serves as a key biosynthetic precursor for anthraquinones in some …
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Asperulosidic acid |
| CAS NO. | 25368-11-0 |
| Appearance | White to off-white crystalline powder or lyophilized solid |
| Molecular Formula | C₁₄H₁₆O₉ |
| Molecular Weight | 328.27 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in water, methanol, ethanol, DMSO; sparingly soluble in ethyl acetate; insoluble in non-polar solvents |
| Endotoxin | <0.1 EU/mg |
| Biological Activity | Exhibits anti-inflammatory, antioxidant, and potential neuroprotective activities in preclinical studies |
| Storage Conditions | - Solid: 2–8°C, sealed, dry, protected from light and moisture- Solution: -80°C (long-term storage, ≤6 months); -20°C (short-term, ≤1 month) |
| Stock Location | Stock in USA |
| MOQ | 10g |
1.MECHANISM OF ACTION
- Potent Anti-inflammatory Action: It inhibits the production of pro-inflammatory mediators, such as nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β), by suppressing the activation of the NF-κB and MAPK (p38, JNK, ERK) signaling pathways. It also downregulates the expression of inducible enzymes like inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2).
- Antioxidant Activity: It acts as a free radical scavenger, reducing oxidative stress. It also enhances the activity of endogenous antioxidant enzymes (e.g., superoxide dismutase, catalase, glutathione peroxidase) by activating the Nrf2/ARE signaling pathway.
- Hepatoprotection: It protects liver cells from toxin-induced damage (e.g., from CCl₄, acetaminophen) by reducing oxidative stress, inhibiting inflammation, and modulating apoptotic pathways.
2.PRODUCT INDICATIONS
- Inflammation & Immunology Research: As a potent natural NF-κB/MAPK inhibitor for studying chronic inflammatory diseases, such as arthritis, colitis, hepatitis, and atherosclerosis.
- Hepatology & Liver Research: For investigating natural hepatoprotective agents against chemical-induced liver injury, fibrosis, and non-alcoholic fatty liver disease (NAFLD).
- Oncology Research: Studying its anti-proliferative and pro-apoptotic mechanisms in various cancer models.
- Metabolic Disease Research: Investigating its potential benefits in type 2 diabetes and metabolic syndrome.
- Natural Product & Phytochemistry: As a high-purity reference standard for the authentication, quantification, and quality control of herbal products derived from Morinda citrifolia(Noni), Gardenia jasminoides, and other iridoid-containing plants.
- Nutraceutical Development: As a marker compound for standardizing Noni-based dietary supplements.
3.CLINICAL EFFICACY OF PRODUCT
- Robust Preclinical Efficacy: Numerous in vitro and in vivo studies have conclusively demonstrated its significant anti-inflammatory, hepatoprotective, and antioxidant efficacy in animal models of respective diseases.
- Traditional Medicine Validation: Plants rich in asperulosidic acid, such as Noni (Morinda citrifolia), have a long history of traditional use for a wide range of ailments, including inflammation, pain, and infections, providing ethnopharmacological support for its bioactivity.
- Clinical Relevance of Source Plants: Noni juice, which contains asperulosidic acid, has been studied in human clinical trials. Some trials suggest potential benefits on joint health, physical endurance, and immune function, though more rigorous studies are needed. Asperulosidic acid is considered a key active constituent contributing to these effects.
- Research Significance: Its identification as a major active component drives the scientific validation of traditional remedies. Its high purity allows for precise mechanistic studies and serves as an essential benchmark for herbal product standardization.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
4.Certificate
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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