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Chemicals
Atosiban Acetate CAS NO.90779-69-4
<p>Atosiban Acetate is a potent synthetic peptide specifically designed as a competitive antagonist for oxytocin and vasopressin receptors. It serves as a highly effective tocolytic agent, rapidly inhibiting preterm uterine contractions to delay imminent labor in pregnant women. Compared to traditional beta-agonists, this compound offers the distinct advantage of significantly fewer maternal cardiovascular side effe…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Atosiban Acetate |
| CAS NO. | 90779-69-4 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C43H67N11O12S2 |
| Molecular Weight | 994.19 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water and aqueous buffers; slightly soluble in methanol, insoluble in organic solvents like ethanol or acetone |
| Endotoxin | < 10 EU/mg (or as specified per pharmacopeial standards) |
| Biological Activity | Potent and selective competitive antagonist of oxytocin receptors; inhibits uterine contractions by blocking oxytocin-mediated signaling pathways |
| Storage Conditions | Store at 2–8°C, protected from light and moisture; avoid freezing |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The therapeutic action of Atosiban centers on its competitive blockade of oxytocin receptors in the uterine myometrium and decidua. By occupying these receptors, it prevents oxytocin from triggering the release of inositol trisphosphate, thereby reducing intracellular calcium mobilization and the influx of extracellular calcium ions. This cascade effectively suppresses uterine smooth muscle contractions and inhibits the release of prostaglandins E and F, leading to rapid uterine relaxation and sustained quiescence shortly after administration.
2.PRODUCT INDICATIONS
This product is clinically indicated for women experiencing threatened preterm labor between 24 and 33 weeks of gestation, specifically those presenting with regular uterine contractions lasting at least 30 seconds occurring four or more times every 30 minutes, accompanied by cervical dilation of 1–3 cm and effacement of at least 50%. It is particularly suitable for patients with underlying cardiovascular concerns or those who cannot tolerate the side effects of adrenergic tocolytics, providing a vital window for administering corticosteroids to promote fetal lung maturity.
3.Clinical Efficacy of Product
Clinical studies confirm that intravenous Atosiban achieves a significant reduction in uterine contractions within 10 minutes of infusion, maintaining uterine quiescence for extended periods. It has been shown to successfully postpone delivery by at least 48 hours in a substantial proportion of patients, which is critical for completing antenatal corticosteroid therapy. Furthermore, comparative trials demonstrate its efficacy is on par with ritodrine but with a markedly superior cardiovascular safety profile and overall tolerability.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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Global Technology Co., Ltd.
