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Chemicals
Melanotan I CAS NO.75921-69-6
<p>Melanotan I is a synthetic peptide analog of the α-melanocyte stimulating hormone (α-MSH), renowned for its potent melanogenic properties that stimulate skin tanning. Originally researched for photoprotection, it activates melanocytes to increase eumelanin production, offering a sunless tanning effect and potential benefits for skin conditions like erythropoietic protoporphyria. The product appeals to individuals…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Melanotan I |
| Synonyms | Afamelanotide, NDP-MSH, α-MSH analog |
| CAS NO. | 75921-69-6 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₇₈H₁₁₁N₂₁O₁₉ |
| Molecular Weight | 1646.88 g/mol |
| Amino Acid Sequence | Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂ |
| Purity (RP-HPLC) | ≥ 98.0% |
| Purity (SEC-HPLC) | ≥ 99.0% (monomer content) |
| Solubility | Soluble in water or sterile saline; for optimal results, reconstitute in appropriate buffer (e.g., PBS or acetate buffer) |
| Endotoxin | < 1.0 EU/mg (for injectable/research grade) |
| Biological Activity | Potent and selective agonist of the melanocortin 1 receptor (MC1R); stimulates melanogenesis and skin pigmentation in vitro and in vivo models. |
| Storage Conditions | Store at -20°C or below in a dry, dark place. After reconstitution, store at 2-8°C for short-term use or aliquot and freeze at -80°C for long-term stability. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The peptide functions as a non-selective agonist at melanocortin receptors, primarily targeting the MC1R on melanocytes. Upon binding, it triggers intracellular cAMP elevation through G-protein coupled receptor activation, leading to upregulated tyrosinase activity and subsequent melanin synthesis. This receptor-mediated pathway promotes eumelanin production over pheomelanin, resulting in darker pigmentation with potential photoprotective qualities, while also influencing ancillary effects on inflammation and sexual function through cross-reactivity with other melanocortin receptors.
2.PRODUCT INDICATIONS
Melanotan I is utilized in research contexts for investigating pigmentation disorders, photodermatoses, and melanocortin receptor physiology. Its applications extend to experimental studies on sexual dysfunction and inflammatory conditions due to receptor cross-reactivity. The peptide serves as a pharmacological tool for exploring melanogenesis pathways and developing novel therapeutics for skin protection, with particular relevance to fair-skinned populations or patients with light intolerance conditions seeking pigmentation-based solutions.
3.CLINICAL EFFICACY OF PRODUCT
Research demonstrates Melanotan I's capacity to induce significant skin darkening through increased eumelanin production, with studies showing measurable pigmentation changes lasting weeks post-administration. In photodermatosis models, it reduces photosensitivity reactions and minimizes UV-induced damage. Its effects on libido and erectile function observed in early-phase trials, while secondary, contribute to its multifaceted research profile, though variable responses necessitate further investigation into individualized dosing and long-term safety parameters.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Melanotan I, Melanotan-1, Afamelanotide, Melanocortin agonist, Research peptide, Tanning peptide, Skin pigmentation, Photoprotection, α-MSH analog, MC1R agonist, Eumelanin stimulation, Scenesse, Erythropoietic protoporphyria, Cosmetic peptide, CAS 75921-69-6, Research peptide, Pharmaceutical
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Global Technology Co., Ltd.
