Urolithin D CAS NO.131086-98-1

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

Urolithin D functions primarily as a competitive and reversible antagonist of Ephrin type-A receptors (EphA), exhibiting intra-class selectivity that allows it to specifically inhibit EphA2 phosphorylation without interfering with EphB receptors. Additionally, it exerts its biological effects through advanced free radical scavenging mechanisms, including formal hydrogen atom transfer (F-HAT) and single electron transfer followed by proton transfer (SET-PT), effectively neutralizing reactive oxygen species like peroxyl and hydroxyl radicals to mitigate oxidative stress at the cellular level.

2.PRODUCT INDICATIONS

This product is indicated for research applications focused on prostate and colon cancer cell migration inhibition, oxidative stress mitigation in neuronal and muscle tissues, and the modulation of inflammatory pathways. It is particularly suitable for scientists and formulators targeting selective EphA receptor signaling in oncology research, as well as for developing supplements aimed at individuals with compromised gut microbiota who are unable to naturally produce sufficient levels of this metabolite from dietary precursors.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that Urolithin D effectively reduces oxidative DNA damage by targeting 2-deoxyguanosine lesions and exhibits a high rate constant for quenching peroxyl radicals, suggesting a strong potential for cytoprotection. While human clinical trials are more extensive for Urolithin A, the structural features of Urolithin D confer a unique pharmacokinetic profile with high reactivity, supporting its role in enhancing cellular resilience and supporting mitochondrial function in in vitro and animal models of age-related decline.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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