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Chemicals
D-beta- Tocotrienol CAS NO.490-23-3
<p>D-beta-Tocotrienol is a prominent isomer of Vitamin E, primarily found in plant sources like palm oil and rice bran, distinguished by its potent biological activity beyond basic antioxidant functions. It is widely researched for its superior effects in modulating cholesterol metabolism, suppressing cancer cell growth, and protecting neurons from oxidative damage, making it a valuable compound for nutritional bioc…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | D-gamma-Tocopherol |
| Synonyms | / |
| CAS NO. | 490-23-3 |
| Appearance | Pale yellow to light orange oily liquid |
| Molecular Formula | C28H42O2 |
| Molecular Weight | 410.63 g/mol |
| Amino Acid Sequence | Not applicable (Non-peptide compound) |
| Purity (RP-HPLC) | ≥ 98.0% |
| Purity (SEC-HPLC) | ≥ 99.0% (monomer content) |
| Solubility | Soluble in ethanol, DMSO, and vegetable oils; insoluble in water |
| Endotoxin | < 1 EU/mg (or Not detected) |
| Biological Activity | Potent antioxidant; exhibits anticancer, neuroprotective, and cholesterol-lowering effects; modulates HMG-CoA reductase and induces apoptosis in cancer cells |
| Storage Conditions | Store at 2–8°C, protected from light and air |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
D-beta-Tocotrienol exerts its effects by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, a key enzyme in the cholesterol biosynthesis pathway, leading to reduced LDL cholesterol synthesis. It also induces apoptosis in cancer cells by modulating signaling pathways such as PI3K/Akt and NF-κB, and activates the Nrf2 pathway to enhance cellular antioxidant defenses. Its neuroprotective action involves inhibiting c-Src kinase and reducing glutamate-induced cytotoxicity.
2.PRODUCT INDICATIONS
This product is indicated for research applications focused on cardiovascular health, including hypercholesterolemia and atherosclerosis studies, as well as cancer research targeting breast, prostate, and pancreatic malignancies. It is also used in neuroscience to investigate protection against stroke, Alzheimer's disease, and other neurodegenerative conditions. Additionally, it is applied in metabolic disorder research and as a potent antioxidant in models of oxidative stress.
3.CLINICAL EFFICACY OF PRODUCT
Clinical and preclinical studies demonstrate that D-beta-Tocotrienol supplementation significantly lowers total and LDL cholesterol levels in hypercholesterolemic subjects. In cancer models, it inhibits tumor growth and metastasis while inducing apoptosis. Its neuroprotective efficacy is evidenced by reduced infarct volume in stroke models and improved cognitive function in neurodegenerative disease studies, supporting its therapeutic potential for chronic and age-related diseases.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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