20(R)Ginsenoside Rg3 CAS NO.38243-03-7

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

The mechanism of action of 20(R)Ginsenoside Rg3 involves the modulation of key signaling pathways, primarily the PI3K/Akt/mTOR and MAPK/ERK pathways. It exerts its anti-tumor effects by inhibiting the epithelial-mesenchymal transition (EMT) and suppressing the expression of matrix metalloproteinases (MMP-2 and MMP-9), thereby preventing tumor cell invasion and metastasis. In neuroprotection, it attenuates neuronal injury by suppressing autophagy and reducing apoptosis through the upregulation of Bcl-2 and downregulation of Bax and cleaved caspase-3. Additionally, it enhances natural killer (NK) cell activity by increasing the expression of activating receptors and cytolytic molecules via the MAPK/ERK signaling pathway, boosting immune surveillance against cancer cells.

2.PRODUCT INDICATIONS

20(R)Ginsenoside Rg3 is indicated for the clinical treatment and adjuvant therapy of various cancers, including lung cancer, breast cancer, liver cancer, gastric cancer, and colon cancer. It is also used to improve and prevent common age-related conditions such as cardiovascular diseases, coronary heart disease, limb weakness, and memory loss. Furthermore, it exhibits biological activity in antiviral applications, radiosensitization, and the treatment of chronic obstructive pulmonary disease (COPD). The product is suitable for patients undergoing chemotherapy to enhance immune function and improve quality of life, as well as for individuals seeking neuroprotection against ischemic brain injury and hepatoprotection against drug-induced liver damage.

3.CLINICAL EFFICACY OF PRODUCT

Clinical studies and a large body of data confirm that 20(R)Ginsenoside Rg3 effectively inhibits the growth and metastasis of various tumors, significantly improving clinical symptoms and the quality of life for patients. It has been shown to enhance the efficacy of chemotherapy by improving immune function, including humoral and cell-mediated immunity. In neuroprotection, it reduces neuronal damage and motor dysfunction following cerebral ischemia-reperfusion injury. The product also demonstrates hepatoprotective effects by ameliorating acetaminophen-induced liver injury through the suppression of inflammation and apoptosis. Its safety profile is favorable, with a wide therapeutic window and good oral absorption, making it a reliable option for long-term adjuvant therapy.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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