Skimmianine CAS NO.83-95-4

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

The primary mechanism of action of Skimmianine involves the inhibition of acetylcholinesterase (AChE), an enzyme responsible for breaking down the neurotransmitter acetylcholine. By blocking this enzyme, Skimmianine increases acetylcholine levels in the synaptic cleft, which enhances cholinergic transmission. Additionally, it exerts anti-inflammatory effects by modulating intracellular signaling pathways, including the inhibition of histamine release and the activation of the PI3K/Akt pathway, which helps reduce neuroinflammation and oxidative stress.

2.PRODUCT INDICATIONS

Skimmianine is indicated for research and development in areas related to neurological disorders, such as Alzheimer's disease and other conditions associated with cholinergic deficits. It is also used in studies focusing on its analgesic and antispasmodic effects for pain management and muscle relaxation. Furthermore, its cytotoxic properties make it a subject of interest in oncology research for investigating its effects on various cancer cell lines.

3.CLINICAL EFFICACY OF PRODUCT

In preclinical studies, Skimmianine has demonstrated significant efficacy in reducing pain and inflammation in animal models, showing potent analgesic and anti-inflammatory activities. It has also shown neuroprotective effects by mitigating ischemia-reperfusion injury and reducing neuroinflammation through the NF-κB pathway. While clinical data in humans is limited, its strong acetylcholinesterase inhibitory activity suggests potential therapeutic benefits for cognitive enhancement and neurodegenerative diseases

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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