Chemicals

3′-O-Angeloylhamaudol CAS NO.84272-84-4

<p>3&#39;-O-Angeloylhamaudol is a natural chromone compound primarily isolated from the roots of <em>Angelica japonica</em>and <em>Saposhnikovia divaricata</em>. It is characterized by its high purity and stability, making it a valuable reference standard for quality control in herbal medicine research. This compound is known for its dual-action mechanism, combining anti-angiogenic effects with immune system modulat…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
3'-O-Angeloylhamaudol
CAS NO.
84272-84-4
Appearance
White to off-white powder
Molecular Formula
C20H22O6
Molecular Weight
358.39 g/mol
Purity (RP-HPLC)
≥98%
Solubility

Soluble in DMSO, methanol; slightly soluble in water; insoluble in hexane

Endotoxin< 0.01 EU/mg (LAL test)
Biological Activity
Inhibits VEGFR-2 phosphorylation; modulates intestinal intraepithelial lymphocyte activity
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The compound exerts its effects through a dual mechanism: it inhibits tumor-induced angiogenesis by blocking the phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) in endothelial cells, thereby cutting off the blood supply to tumors. Simultaneously, it activates intestinal intraepithelial lymphocytes, enhancing the body's immune surveillance and response against cancerous cells, which is particularly effective in models like colon 26-bearing mice.

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2.PRODUCT INDICATIONS

3'-O-Angeloylhamaudol is indicated for research into anti-tumor and anti-inflammatory therapies. It is particularly relevant for studies focusing on colon cancer and gastric adenocarcinoma, where its ability to inhibit cell growth and modulate immune responses is most pronounced. Researchers in oncology and immunology use this compound to explore its potential in developing new treatments for solid tumors and inflammatory conditions.

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3.CLINICAL EFFICACY OF PRODUCT

In preclinical studies, 3'-O-Angeloylhamaudol has demonstrated significant anti-tumor efficacy by effectively inhibiting tumor growth in animal models. It has shown promising results in reducing tumor size and metastasis through its anti-angiogenic properties and immune activation. While clinical data in humans is still emerging, the compound's strong performance in laboratory settings positions it as a promising candidate for further clinical development in cancer therapy.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags:3'-O-Angeloylhamaudol, Anti-tumor, Anti-angiogenesis, Immune Activation, Natural Product, Chromone, Angelica Japonica, Research Use Only,Supplier, Manufacturer, Bulk order,  Pharmaceutical.


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