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Chemicals
Quercetin-3-O-sophoroside CAS NO.18609-17-1
<p><strong>Quercetin-3-O-sophoroside</strong> (CAS NO. 18609-17-1) is a high-purity, naturally occurring <strong>flavonol glycoside</strong> isolated from various plants, such as onions, buckwheat, and other botanicals. It is a water-soluble derivative of the flavonol quercetin, where the sugar moiety <strong>sophorose</strong> (a disaccharide of two glucose units) is attached at the 3-hydroxyl position. This glycos…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Quercetin-3-O-sophoroside |
| CAS NO. | 18609-17-1 |
| Appearance | Yellow to light yellow crystalline powder |
| Molecular Formula | C₂₇H₃₀O₁₆ |
| Molecular Weight | 610.51 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | - DMSO: ≥10 mg/mL (with sonication) - Methanol/ethanol: Moderately soluble - Poorly soluble in water |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Exhibits antioxidant, anti-inflammatory, anti-tumor, and hepatoprotective activities; acts as a free radical scavenger; isolated from various plants including Sophora japonica and Ginkgo biloba. |
| Storage Conditions | - Solid: -20°C (or 2–8°C for short-term), protect from light, sealed dry storage- In solution: -80°C for 6–12 months; -20°C for 1 month; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
- Potent Antioxidant Activity: It directly scavenges reactive oxygen and nitrogen species (ROS/RNS) and acts as a metal chelator. It also upregulates endogenous antioxidant defenses via the Nrf2/ARE pathway, increasing the expression of enzymes like heme oxygenase-1 (HO-1) and glutathione peroxidase.
- Anti-inflammatory Action: It inhibits the production of pro-inflammatory mediators (NO, PGE2, TNF-α, IL-6) by suppressing the activation of the NF-κB and MAPK signaling pathways.
- Anti-diabetic Effects: It inhibits carbohydrate-digesting enzymes (α-amylase, α-glucosidase), reducing postprandial blood glucose spikes. It also improves insulin sensitivity and protects pancreatic β-cells.
- Vasoprotective Effects: It improves endothelial function by promoting nitric oxide (NO) production and reducing oxidative stress in blood vessels.
2.PRODUCT INDICATIONS
- Nutraceutical & Functional Food Development: As a standardised active ingredient in dietary supplements and foods targeting oxidative stress, inflammation, metabolic health, and cardiovascular support.
- Anti-diabetic Research: For studying natural inhibitors of carbohydrate digestion and modulators of glucose metabolism.
- Anti-inflammatory & Antioxidant Research: Investigating natural compounds for chronic inflammatory and oxidative stress-related diseases.
- Cosmetic Science: As an active in skincare products for its antioxidant and anti-aging properties.
- Phytochemistry & Analytical Chemistry: As a reference standard for the identification, quantification, and quality control of quercetin glycosides in plant extracts, foods, and herbal products.
3.CLINICAL EFFICACY OF PRODUCT
- Epidemiological Evidence: High dietary intake of quercetin-rich foods (like onions, containing this glycoside) is associated with a reduced risk of cardiovascular diseases, certain cancers, and type 2 diabetes.
- Bioavailability & Activity: Though less studied individually than quercetin, its glycosylated form is considered a major bioavailable form in the diet. Human studies on quercetin supplements show:
- Reduction in blood pressure in hypertensive patients.
- Improvement in endothelial function and reduction in inflammatory markers.
- Anti-viral activity and reduction in upper respiratory tract infection severity.
- Research Significance: As a specific, high-purity glycoside, it allows for precise research into the structure-activity relationships of flavonoid glycosides, their bioavailability, and their distinct biological effects compared to the aglycone
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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